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pro vyhledávání: '"Cynthia Sakofsky"'
Autor:
Cynthia Sakofsky, Kivin Jacobsen, Vadir Lopez-Salmeron, Margaret Nakamoto, Liselotte Brix, Aruna Ayer
Publikováno v:
The Journal of Immunology. 208:173.08-173.08
The advancement of immunotherapies and drug development relies on the characterization of antigen-specific T cells. However, due to their low frequency among T cells and their inherent weak affinity to bind known MHC-peptide complexes, detection of t
Autor:
Cynthia Sakofsky, Kivin Jacobsen, Vadir Lopez-Salmeron3, Margaret Nakamoto, Liselotte Brix, Stefanie Mortimer
Publikováno v:
The Journal of Immunology. 206:27.03-27.03
Adoptively transferred antigen-specific T cells have shown great efficacy in treatment of some virus-associated diseases and malignancies. A major driver of the development of adoptive T-cell therapy has been our ability to successfully characterize