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Autor:
George R. Breese, Sophia T. Papadeas, Christopher Halloran, Thomas J. McCown, Bonita L. Blake
Publikováno v:
The Journal of Comparative Neurology. 511:271-285
Rats lesioned with 6-hydroxydopamine (6-OHDA) as neonates exhibit behavioral and neurochemical abnormalities in adulthood that mimic Lesch-Nyhan disease, schizophrenia and other developmental disorders of frontostriatal circuit dysfunction. In these
Publikováno v:
The Journal of Comparative Neurology. 495:299-313
The nucleus accumbens (Acb) shell and core are essential components of neural circuitry mediating the reward and motor effects produced by activation of dopamine D2 or cannabinoid-1 (CB1) receptors. D2 receptors can form heterodimeric complexes with
Publikováno v:
The Journal of Comparative Neurology. 433:193-207
α-2A-adrenergic receptor (α2A-AR) agonists modulate diverse autonomic functions. These actions are believed to involve functionally specialized, second-order neurons in catecholamine-containing portions of the medial nucleus tractus solitarius (mNT
Publikováno v:
The Journal of Comparative Neurology. 373:433-450
The existence of possible relationships among the developmental profile of various cholinergic markers in the main olfactory bulb (OB) was assessed by using in vitro quantitative autoradiography. Muscarinic receptors were visualized with [3H]pirenzep
Publikováno v:
The Journal of Comparative Neurology. 345:46-68
The mu (mu) opioid receptors, which mediate the effects of morphine, are widely distributed in brain. We have examined the distribution of mRNA encoding a mu opioid receptor in rat brain with in situ hybridization histochemistry at the single-cell le
Publikováno v:
The Journal of Comparative Neurology. 333:94-108
The laminar distribution and morphological structures associated with GABAA receptor immunoreactivity in the cat visual cortex were studied by using two different polyclonal antibodies directed either against the purified GABAA receptor protein (anti
Autor:
Jörn Schäper, Michael Schäfer, Helmut Habazettl, Hashim Abdul-Khaliq, Wei Huang, Sascha Treskatsch, Shaaban A. Mousa, Mohammed Shaqura
Publikováno v:
The Journal of comparative neurology. 518(18)
Recent interest has been focused on the opioid regulation of heart performance; however, specific allocation of opioid receptors to the parasympathetic, sympathetic, and sensory innervations of the heart is scarce. Therefore, the present study aimed
Autor:
Kate M Hatzopoulos, Erica L. Fletcher, Laura E Downie, Jennifer L. Wilkinson-Berka, Algis J. Vingrys, Michael J. Pianta, Michael Kalloniatis
Publikováno v:
The Journal of comparative neurology. 518(1)
Retinopathy of prematurity (ROP) is characterized by deficits in the scotopic pathway, although the cellular locus for these deficits is not clear. Here we examined neurochemical and cellular changes that develop during oxygen-induced retinopathy, a
Autor:
Amor Belmeguenai, Pascal E. Sanchez, Laurent Bezin, Anne Morales, Fabrice Navarro, Jacques Bodennec, Philippe Ryvlin, Béatrice Georges, Colette Moulin, Chantal Bonnet, Raafat P. Fares, Jérémie Nadam, Marion Le Cavorsin
Publikováno v:
The Journal of comparative neurology. 514(4)
Brain effects of erythropoietin (Epo) are proposed to involve a heteromeric receptor comprising the classical Epo receptor (Epo-R) and the common beta chain (betac). However, data documenting the pattern of betac gene expression in the healthy brain,
Autor:
Charlotte Cornil, Gregory F. Ball
Publikováno v:
The Journal of comparative neurology. 511(5)
Dopaminergic and adrenergic receptors are G-protein-coupled receptors considered to be different based on their pharmacology and signaling pathways. Some receptor subtypes that are members of one family are actually closer in phylogenetic terms to so