Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Shannon R. Morris"'
Autor:
Laurel M. Adams, Lyndon C. Kirby, Robert A. Blum, Christian D. Lates, Derek J. Eberwein, Sharon C. Murray, Ke Zhang, Shannon R. Morris, Brendan M. Johnson
Publikováno v:
The Journal of Clinical Pharmacology. 50:566-575
Casopitant, a novel NK-1 receptor antagonist under investigation for the prevention of postoperative and chemotherapy-induced nausea and vomiting, is a weak to moderate inhibitor of CYP3A and a moderate inducer of CYP2C9 in vitro. Furthermore, both C