Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sine Reker Hadrup"'
Autor:
Nikolaj Pagh Kristensen, Christina Heeke, Siri A. Tvingsholm, Annie Borch, Arianna Draghi, Michael D. Crowther, Ibel Carri, Kamilla K. Munk, Jeppe Sejerø Holm, Anne-Mette Bjerregaard, Amalie Kai Bentzen, Andrea M. Marquard, Zoltan Szallasi, Nicholas McGranahan, Rikke Andersen, Morten Nielsen, Göran B. Jönsson, Marco Donia, Inge Marie Svane, Sine Reker Hadrup
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 2 (2022)
BACKGROUND Neoantigen-driven recognition and T cell–mediated killing contribute to tumor clearance following adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TILs). Yet how diversity, frequency, and persistence of expanded neoepitop
Externí odkaz:
https://doaj.org/article/d770acf332f045ffaf6a8379f97a7b0f
Autor:
Morten Nielsen, Nicholas McGranahan, Anne-Mette Bjerregaard, Marco Donia, Inge Marie Svane, Sine Reker Hadrup, Jeppe Sejerø Holm, Amalie Kai Bentzen, Siri A. Tvingsholm, Zoltan Szallasi, Göran Jönsson, Christina Heeke, Kamilla K Munk, Arianna Draghi, Ibel Carri, Nikolaj Pagh Kristensen, Andrea Marion Marquard, Annie Borch, Rikke Andersen, Michael D. Crowther
Publikováno v:
The Journal of Clinical Investigation
Kristensen, N P, Heeke, C, Tvingsholm, S A, Borch, A, Draghi, A, Crowther, M D, Carri, I, Munk, K K, Holm, J S, Bjerregaard, A-M, Bentzen, A K, Marquard, A M, Szallasi, Z, McGranahan, N, Andersen, R, Nielsen, M, Jönsson, G B, Donia, M, Svane, I M & Hadrup, S R 2022, ' Neoantigen-reactive CD8+ T cells affect clinical outcome of adoptive transfer with tumor-infiltrating lymphocytes in melanoma ', Journal of Clinical Investigation, vol. 132, no. 2 . https://doi.org/10.1172/JCI150535
Kristensen, N P, Heeke, C, Tvingsholm, S A, Borch, A, Draghi, A, Crowther, M D, Carri, I, Munk, K K, Holm, J S, Bjerregaard, A M, Bentzen, A K, Marquard, A M, Szallasi, Z, McGranahan, N, Andersen, R, Nielsen, M, Jönsson, G B, Donia, M, Svane, I M & Hadrup, S R 2022, ' Neoantigen-reactive CD8 + T cells affect clinical outcome of adoptive cell therapy with tumor-infiltrating lymphocytes in melanoma ', Journal of Clinical Investigation, vol. 132, no. 2, 150535, pp. 1-16 . https://doi.org/10.1172/JCI150535
Kristensen, N P, Heeke, C, Tvingsholm, S A, Borch, A, Draghi, A, Crowther, M D, Carri, I, Munk, K K, Holm, J S, Bjerregaard, A-M, Bentzen, A K, Marquard, A M, Szallasi, Z, McGranahan, N, Andersen, R, Nielsen, M, Jönsson, G B, Donia, M, Svane, I M & Hadrup, S R 2022, ' Neoantigen-reactive CD8+ T cells affect clinical outcome of adoptive transfer with tumor-infiltrating lymphocytes in melanoma ', Journal of Clinical Investigation, vol. 132, no. 2 . https://doi.org/10.1172/JCI150535
Kristensen, N P, Heeke, C, Tvingsholm, S A, Borch, A, Draghi, A, Crowther, M D, Carri, I, Munk, K K, Holm, J S, Bjerregaard, A M, Bentzen, A K, Marquard, A M, Szallasi, Z, McGranahan, N, Andersen, R, Nielsen, M, Jönsson, G B, Donia, M, Svane, I M & Hadrup, S R 2022, ' Neoantigen-reactive CD8 + T cells affect clinical outcome of adoptive cell therapy with tumor-infiltrating lymphocytes in melanoma ', Journal of Clinical Investigation, vol. 132, no. 2, 150535, pp. 1-16 . https://doi.org/10.1172/JCI150535
Background Neoantigen-driven recognition and T cell-mediated killing contribute to tumor clearance following adoptive cell therapy (ACT) with Tumor-Infiltrating Lymphocytes (TILs). Yet, how diversity, frequency, and persistence of expanded neoepitope
Autor:
Jennifer J. Gray, John J. Erickson, Kathryn M. Edwards, Xinnan Niu, Jack R. Bennink, Sebastian Joyce, John V. Williams, William H. Hildebrand, Timothy M. Hill, Carla Oseroff, Andrew J. Link, K. Jill McAfee, Ton N. Schumacher, Pavlo Gilchuk, Stephanie B. Conant, Kelli L. Boyd, Søren Buus, Alessandro Sette, James E. Crowe, Mu Zheng, Charles T. Spencer, Sine Reker Hadrup
Publikováno v:
The Journal of clinical investigation. 123(5)
CD8+ T cells (TCD8) confer protective immunity against many infectious diseases, suggesting that microbial TCD8 determinants are promising vaccine targets. Nevertheless, current T cell antigen identification approaches do not discern which epitopes d