Zobrazeno 1 - 10
of 92
pro vyhledávání: ''
Autor:
Kenneth D. Roth, Valentina Pirro, Kevin L. Duffin, Jonathan M. Wilson, Yanzhu Lin, Jill A. Willency, Axel Haupt, Paul L. Milligan, Christopher B. Newgard, Giacomo Ruotolo
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 107:363-378
Context Tirzepatide substantially reduced hemoglobin A1c (HbA1c) and body weight in subjects with type 2 diabetes (T2D) compared with the glucagon-like peptide 1 receptor agonist dulaglutide. Improved glycemic control was associated with lower circul
Autor:
Giulio Mengozzi, Valeria Avataneo, Paolo Mulatero, Franco Rabbia, Silvia Monticone, Jacopo Burrello, Fabrizio Buffolo, Franco Veglio, Alessio Pecori, Francesca Rumbolo, Antonio D'Avolio, Chiara Bertello
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 106:e3655-e3664
Context Although current international guidelines recommend to avoid mineralocortcoid receptor antagonists in patients undergoing screening test for primary aldosteronism, a recent report suggested that mineralocorticoid receptor antagonist treatment
Autor:
Scott Akker, Sarah Pitkin, Mona Waterhouse, Matthew Matson, Teng-Teng Chung, Wing-Chiu Sze, Maralyn Druce, Anju Sahdev, Sam O’Toole, Anne Dawnay, Laila Parvanta, William Drake
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 105:e3776-e3784
Context In primary aldosteronism, cosecretion of cortisol may alter cortisol-derived adrenal venous sampling indices. Objective To identify whether cortisol cosecretion in primary aldosteronism alters adrenal venous sampling parameters and interpreta
Autor:
Leanne Hodson, Sarah White, Nikolaos Nikolaou, Craig Webster, Andrea M. Isidori, Joanne E Duffy, Ilaria Bonaventura, Ahmad Moolla, Jonathan Hazlehurst, Thomas Marjot, Riccardo Pofi, Conor Woods, Thomas Cornfield, Jeremy W. Tomlinson, Nantia Othonos
Publikováno v:
J Clin Endocrinol Metab
Context Glucocorticoids (GCs) are commonly prescribed, but their use is associated with adverse metabolic effects. 5α-reductase inhibitors (5α-RI) are also frequently prescribed, mainly to inhibit testosterone conversion to dihydrotestosterone. How
Autor:
Kinga Németh, Lilla Reiniger, Borbála Szabó, Hajnalka Rajnai, Henriett Butz, Lilla Krokker, Katalin Mészáros, Attila Patócs, Sándor Czirják, Ildikó Krencz, Nikolette Szücs, Katalin Karaszi
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 105:2015-2026
Background Cytosine intermediaries 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC), epigenetic hallmarks, have never been investigated in pituitary neuroendocrine tumors (PitNET). Objective To examine methylation-demethylation status of glo
Autor:
Sabine Kahl, Dan Ziegler, Yanislava Karusheva, Sandra Trenkamp, Pavel Bobrov, Michael Roden, Georgia Kanti, Oana P Zaharia, Volker Burkart, Theresia Sarabhai, Daniel F Markgraf, Evrim Anadol-Schmitz, Julia Szendroedi, Klaus Strassburger
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 105:e2222-e2231
Context Vitamin B12 and folate deficiency are not only linked to hematological, neurological, and cardiovascular diseases, but are also associated with insulin resistance. Metformin can decrease vitamin B12 and folate concentrations. Objective To exa
Autor:
Richard D. Gordon, Ashraf H. Ahmed, Jacobus P.J. Ungerer, Michael Stowasser, Martin Wolley, Zeng Guo, Marko Poglitsch, Brett McWhinney
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 103:3965-3973
Context Current threshold values for primary aldosteronism (PA) diagnostic testing are based on measuring aldosterone (PAC) using immunoassays. Quantification of PAC by liquid chromatography-tandem mass spectrometry (LC-MS/MS) yields lower values. Ob
Autor:
Iain K. Haitsma, Sebastian J C M M Neggers, Joseph A M J L Janssen, Alof H G Dallenga, Patric J.D. Delhanty, Aart Jan van der Lely, Ammar Muhammad
Publikováno v:
Journal of Clinical Endocrinology and Metabolism, 103(2), 586-595. Endocrine Society
Aim: To assess the efficacy and safety of pasireotide long-Acting release (PAS-LAR) alone or in combination with pegvisomant by switching patients with acromegaly who were well controlled with long-Acting somatostatin analogues (LA-SSAs) and pegvisom
Autor:
M. Montini, Gherardo Mazziotti, Renato Cozzi, Salvatore Cannavò, Enza Gatti, Filippo Maffezzoni, Ezio Ghigo, Giorgio Arnaldi, Anna Maria Formenti, Silvia Grottoli, Diego Ferone, Giovanna Bugari, Pietro Maffei, Massimo Terzolo, Andrea Giustina, Roberto Castello
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 102:2454-2464
Context: Increase in drug frequency or dose is recommended for acromegaly patients with partial response to long-acting somatostatin receptor ligands (SRLs). However, the efficacy and safety data with lanreotide (LAN) Autogel (LAN-ATG) at high dose (
Autor:
Husam Ghanim, Nitesh D. Kuhadiya, Aditya Mehta, Manisha Garg, Ajay Chaudhuri, Manav Batra, Salman Khan, Paresh Dandona, Antoine Makdissi, Barrett Torre, Jeanne Hejna
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 101:3506-3515
It is imperative that novel approaches to treatment of type 1 diabetes (T1D) are devised.The objective of the study was to investigate whether addition of dapagliflozin to insulin and liraglutide results in a significant reduction in glycemia and bod