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Autor:
Francesca Zerbini, Mattia Pizzi, Silvia Perra, Stefano Ciardullo, Alberto Binda, Gianluca Perseghin, Emanuele Muraca, Guido Lattuada, Matteo Villa, Eleonora Bianconi, Pietro Pizzi, Rosa Cannistraci, Giuseppina Manzoni, Alice Oltolini
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 106:e3087-e3097
Context Laparoscopic sleeve gastrectomy (LSG) is a recognized effective procedure of bariatric surgery, but a poor response in weight loss may still represent a clinical problem. To date there are no validated predictors useful to better perform pati
Autor:
Diane M. Comer, Steve N. Caritis, Kaleab Z. Abebe, Christina M. Scifres, Maisa Feghali, Jacqueline Atlass, Janet M. Catov, Silva A. Arslanian
Publikováno v:
J Clin Endocrinol Metab
Background Gestational diabetes mellitus (GDM) is associated with fetal overgrowth, and certain treatments are associated with an increased risk of macrosomia. However, there are limited data about the long-term effect of GDM treatment on childhood g
Publikováno v:
The Journal of Clinical Endocrinology and Metabolism
Objective To evaluate the efficacy of insulin sensitizers on menstrual frequency, sex hormone, and metabolic parameters in overweight women with polycystic ovary syndrome (PCOS). Methods We searched multiple databases from inception to September 2019
Autor:
Frank L. Greenway, Mark G. Haussmann, Karl A. LeBlanc, Eric Ravussin, Charmaine S. Tam, Leanne M. Redman
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 101:3755-3764
CONTEXT: It is not known whether the magnitude of metabolic adaptation, a greater than expected drop in energy expenditure, depends on the type of bariatric surgery and is associated with cardiometabolic improvements. OBJECTIVE: To compare changes in
Autor:
Neda Rasouli, Philip A. Kern, Christopher Erickson, Brooke C. Bredbeck, Helen M. Lawler, Chantal Underkofler
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 101:1422-1428
A substantial number of obese individuals are relatively insulin sensitive and the etiology for this variation remains unknown.The primary objective was to detect factors in adipose tissue differentiating obese insulin-sensitive (OBIS) from obese ins
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 100:E1225-E1233
Roux-en-Y gastric bypass (RYGB) is the most effective treatment for morbid obesity and resolution of diabetes. Over the last decade, it has become well accepted that this resolution of diabetes occurs before significant weight loss; however, the mech
Autor:
Ksenia Sevastianova, Marju Orho-Melander, Hannele Yki-Järvinen, Nina Lundbom, Per-Henrik Groop, Sanja Sädevirta, Carol Forsblom, Gemma Llauradó, Antti Hakkarainen
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 100:607-616
Patients with type 1 diabetes mellitus (T1DM) lack the portal/peripheral insulin gradient, which might diminish insulin stimulation of hepatic lipogenesis and protect against development of nonalcoholic fatty liver disease (NAFLD). We compared liver
Autor:
Barbara A. Gower, Norman K. Pollock, Thomas L. Clemens, Laura Lee Goree, Wesley M. Granger, Krista Casazza
Publikováno v:
The Journal of Clinical Endocrinology and Metabolism
Animal studies indicate that osteocalcin (OC), particularly the undercarboxylated isoform (unOC), affects insulin sensitivity and secretion, but definitive data from humans are lacking.The objectives of the study were to determine whether total OC an
Autor:
Barbara Wolters, Nina Lass, Felix G. Riepe, Thomas Reinehr, Maik Welzel, Alexandra Kulle, Paul-Martin Holterhus
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 98:E1022-E1030
Little information is available on the steroid hormone profiles in obese children and their changes after weight loss.We compared liquid chromatography-tandem mass spectrometry of serum steroid hormone profiles between obese and normal-weight childre
Autor:
Chang-Hsun Hsieh, Nain Feng Chu, Po-Shiuan Hsieh, Chien-Hsing Lee, Yi Jen Hung, Yi Shing Shieh, Fone Ching Hsiao, Yuh Feng Lin
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 98:E267-E274
Growth arrest-specific 6 (Gas6) is a vitamin K-dependent protein secreted by immune cells, endothelial cells, vascular smooth muscle cells, and adipocytes. Preclinical studies indicate that Gas6 and its receptors of the TAM (Tyro-3, Axl, Mer) family