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Autor:
Jean-Marc Kaufman, Michela Villani, Giulia Faccin, Enzo Bonora, Matteo Migazzi, Sabrina Garofalo, Flavia Tosi, Tom Fiers, Paolo Moghetti
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 106:e3414-e3425
Context Few studies have explored in vivo insulin action on substrate use in women with PCOS. In particular, no data are available in women with different PCOS phenotypes. Objective The aim of the study was to evaluate insulin action on glucose (Gox)
Autor:
Timothy W. Jones, Carmel E. Smart, Amelia J. Harray, Nirubasini Paramalingam, Bruce R. King, Grant J. Smith, Barbara Keating, Elizabeth A. Davis
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 106:e3611-e3618
Context The pattern and quantity of insulin required for high-protein high-fat (HPHF) meals is not well understood. Objective This study aimed to determine the amount and delivery pattern of insulin required to maintain euglycemia for 5 hours after c
Autor:
John P. Kirwan, Juan Pablo Del Rincon, Sangeeta R. Kashyap, Stacy A. Brethauer, Steven K. Malin, Christopher L. Axelrod, Emily L. Kullman, Kathryn Pergola, Wagner S Dantas, Philip R. Schauer
Publikováno v:
J Clin Endocrinol Metab
Introduction Patients with type 2 diabetes experience resolution of hyperglycemia within days after Roux-en-Y gastric bypass (RYGB) surgery. This is attributed, in part, to enhanced secretion of hindgut factors following exclusion of the gastric remn
Autor:
Francesca Zerbini, Mattia Pizzi, Silvia Perra, Stefano Ciardullo, Alberto Binda, Gianluca Perseghin, Emanuele Muraca, Guido Lattuada, Matteo Villa, Eleonora Bianconi, Pietro Pizzi, Rosa Cannistraci, Giuseppina Manzoni, Alice Oltolini
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 106:e3087-e3097
Context Laparoscopic sleeve gastrectomy (LSG) is a recognized effective procedure of bariatric surgery, but a poor response in weight loss may still represent a clinical problem. To date there are no validated predictors useful to better perform pati
Autor:
Andreas Peter, Hans-Ulrich Häring, Martin Heni, Corinna Dannecker, Norbert Stefan, Andreas L. Birkenfeld, Julia Hummel, Robert Wagner, Andreas Vosseler, Andreas Fritsche
Publikováno v:
J. Clin. Endocrinol. Metab. 106, 1576-1584 (2021)
The Journal of Clinical Endocrinology and Metabolism
The Journal of Clinical Endocrinology and Metabolism
Context Pharmacological lowering of low-density lipoprotein (LDL) cholesterol potently reduces cardiovascular risk while concurrently increasing type 2 diabetes risk. Objective The aim of this study was to investigate the relationship between LDL cho
Autor:
Dana Dabelea, Wei Perng, Katherine A. Sauder, Lizan D. Bloemsma, John Carey, Michaela P Palumbo, Deborah H. Glueck
Publikováno v:
J Clin Endocrinol Metab
Context It is unclear how fat mass accretion in early life is related to glucose–insulin homeostasis. Objective Examine associations of fat and fat-free mass accretion from birth to early childhood with glucose–insulin homeostasis in early childh
Autor:
Adrian Vella, Giuseppe De Nicolao, John G. Jones, Marcello C. Laurenti, James C. Andrews, Robert A. Rizza, Chiara Dalla Man, Aleksey V. Matveyenko, Cristina Barosa, Claudio Cobelli, Kent R. Bailey, Ron T. Varghese
Publikováno v:
J Clin Endocrinol Metab
Objective Pulsatile insulin secretion is impaired in diseases such as type 2 diabetes that are characterized by insulin resistance. This has led to the suggestion that changes in insulin pulsatility directly impair insulin signaling. We sought to exa
Autor:
Ippei Matsumoto, Keiko Kamei, Fumimaru Niwano, Yasunori Taketomo, Hiroshi Ikegami, Yoshihisa Hiromine, Yumiko Kawabata, Shinsuke Noso, Yoshifumi Takeyama, Naru Babaya
Publikováno v:
The Journal of Clinical Endocrinology and Metabolism
ContextThe rate of glucose metabolism changes drastically after partial pancreatectomy.ObjectiveThis work aims to analyze changes in patients’ glucose metabolism and endocrine and exocrine function before and after partial pancreatectomy relative t
Autor:
Meredith Hawkins, Michelle Carey, Laxmi Upadhyay, Akankasha Goyal, Oana A. Sandu, Sandra Aleksic, Bryan Kuo, Raphael Hulkower, Rebekah Gospin, Harry Shamoon, Jee Young You, Eric Lontchi-Yimagou, Ilan Gabriely, William G. Mitchell
Publikováno v:
J Clin Endocrinol Metab
Background Recurrent hypoglycemia blunts counter-regulatory responses to subsequent hypoglycemic episodes, a syndrome known as hypoglycemia-associated autonomic failure (HAAF). Since adrenergic receptor blockade has been reported to prevent HAAF, we
Autor:
Clea D Harris, Christina Kubrak, Andrea Kelly, Denis Hadjiliadis, Marina Cuchel, Saba Sheikh, Marissa J. Kilberg, Darko Stefanovski, Michael R. Rickels, Ronald C. Rubenstein
Publikováno v:
J Clin Endocrinol Metab
Context Oral glucose tolerance test (OGTT)-related hypoglycemia is common in pancreatic-insufficient cystic fibrosis (PI-CF), but its mechanistic underpinnings are yet to be established. Objective To delineate the mechanism(s) underlying OGTT-related