Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Serge Y. Fuchs"'
Publikováno v:
The Journal of biological chemistry. 279(45)
Ubiquitination, endocytosis, and lysosomal degradation of the IFNAR1 (interferon alpha receptor 1) subunit of the type I interferon (IFN) receptor is mediated by the SCFbeta-Trcp (Skp1-Cullin1-F-box protein beta transducin repeat-containing protein)
Autor:
Thomas J. Slaga, Ze'ev Ronai, Vladimir S. Spiegelman, Michele Pagano, Serge Y. Fuchs, Esther Latres, Pete Stavropoulos
Publikováno v:
The Journal of biological chemistry. 276(29)
Activation of Jun N-kinase (JNK) and NF-kappaB transcription factor are the hallmarks of cellular response to stress. Phosphorylation of NF-kappaB inhibitor (IkappaB) by respective stress-inducible kinases (IKK) is a key event in NF-kappaB activation
Autor:
Serge Y. Fuchs, Hua Lu, Lois Resnick-Silverman, Yahong Lin, Nadia Aithmitti, Ze'ev Ronai, Thomas Buschmann, James J. Manfredi, Xiangwei Wu
Publikováno v:
The Journal of biological chemistry. 276(17)
Regulation of the stability of p53 is key to its tumor-suppressing activities. mdm2 directly binds to the amino-terminal region of p53 and targets it for degradation through the ubiquitin-proteasome pathway. The coactivator protein TAF(II)31 binds to