Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Christopher J. Schofield"'
Autor:
Kirsty S. Hewitson, Claire Hughes, Jan E. Thirkettle, Christopher J. Schofield, Haren Arulanantham, Nadia J. Kershaw
Publikováno v:
The Journal of biological chemistry. 281(1)
(3R,5R)-Clavulanic acid, a clinically used inhibitor of serine beta-lactamases, is produced by fermentation of Streptomyces clavuligerus. The early steps in clavulanic acid biosynthesis leading to the bicyclic beta-lactam intermediate (3S,5S)-clavami