Zobrazeno 1 - 10
of 294
pro vyhledávání: ''
Autor:
Eilish W. McBurnie, Mariena J. A. van der Plas, Peter J. Bond, Manoj Puthia, Roland G. Huber, Ganna Petruk, Artur Schmidtchen, Jitka Petrlova
Publikováno v:
The Journal of Biological Chemistry
Petrlova, J, Petruk, G, Huber, R G, McBurnie, E W, van der Plas, M J A, Bond, P J, Puthia, M & Schmidtchen, A 2020, ' Thrombin-derived C-terminal fragments aggregate and scavenge bacteria and their proinflammatory products ', The Journal of Biological Chemistry, vol. 295, no. 11, pp. 3417-3430 . https://doi.org/10.1074/jbc.RA120.012741
Petrlova, J, Petruk, G, Huber, R G, McBurnie, E W, van der Plas, M J A, Bond, P J, Puthia, M & Schmidtchen, A 2020, ' Thrombin-derived C-terminal fragments aggregate and scavenge bacteria and their proinflammatory products ', The Journal of Biological Chemistry, vol. 295, no. 11, pp. 3417-3430 . https://doi.org/10.1074/jbc.RA120.012741
Thrombin-derived C-terminal peptides (TCPs), including a major 11-kDa fragment (TCP96), are produced through cleavage by human neutrophil elastase and aggregate lipopolysaccharide (LPS) and the Gram-negative bacterium Escherichia coli. However, the p
Publikováno v:
The Journal of Biological Chemistry
Opportunistic bacteria strategically dampen their virulence to allow them to survive and propagate in hosts. However, the molecular mechanisms underlying virulence control are not clearly understood. Here, we found that the opportunistic pathogen Vib
Autor:
Nicholas J. Harmer, Andrea Kovacs-Simon, Séverine Péchiné, Claire Janoir, Jean François Bruxelle, William J. Bradshaw, K. Ravi Acharya, Stephen L. Michell
Publikováno v:
The Journal of Biological Chemistry
Clostridioides difficile is the primary cause of antibiotic-associated diarrhea and colitis, a healthcare-associated intestinal disease resulting in a significant fatality rate. Colonization of the gut is critical for C. difficile pathogenesis. The b
Autor:
Matthias D. Koch, Courtney K. Ellison, Yuki Sugimoto, Mohamed S. Donia, Zemer Gitai, Benjamin P. Bratton, Robert J. Scheffler
Publikováno v:
The Journal of Biological Chemistry
Pseudomonas aeruginosa is a significant threat in both healthcare and industrial biofouling. Surface attachment of P. aeruginosa is particularly problematic as surface association induces virulence and biofilm formation, which hamper later antibiotic
Publikováno v:
J Biol Chem
Aspergillus terreus is an allergenic fungus, in addition to causing infections in both humans and plants. However, the allergens in this fungus are still unknown, limiting the development of diagnostic and therapeutic strategies. We used a proteomic
Autor:
Christian M. Lange, Robert Tampé, Markus Schneider, Georg Dultz, Stefan Zeuzem, Antoine Marion, Ricardo M. Biondi, Tetsuro Shimakami, Tobias M. Zeitler, Rebecca M. Richter, Iris Antes, Christoph Welsch, Christian Grimm, Claudia Stross, Kazuhisa Murai, Daisuke Yamane, Min Kyung Yi, Katrin Bäumer
Publikováno v:
J Biol Chem
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Inhibitors against the NS3-4A protease of hepatitis C virus (HCV) have proven to be useful drugs in the treatment of HCV infection. Although variants have been identified with mutations that confer resistance to these inhibitors, the mutations do not
Autor:
Yoshiharu Matsuura, Koshiro Tabata, William W. Hall, Michael J. Carr, Yasuko Orba, Jody Hobson-Peters, Takasuke Fukuhara, Yuji Wada, Hirofumi Sawa, Ayato Takada, Michihito Sasaki, Roy A. Hall, Shiho Torii
Publikováno v:
J Biol Chem
Chikungunya fever is a re-emerging zoonotic disease caused by chikungunya virus (CHIKV), a member of the Alphavirus genus in the Togaviridae family. Only a few studies have reported on the host factors required for intracellular CHIKV trafficking. He
Autor:
Daniel P. Canniffe, Jennifer L. Thweatt, Donald A. Bryant, Aline Gomez Maqueo Chew, C. Neil Hunter
Publikováno v:
The Journal of Biological Chemistry
Journal of Biological Chemistry
JOURNAL OF BIOLOGICAL CHEMISTRY
Journal of Biological Chemistry
JOURNAL OF BIOLOGICAL CHEMISTRY
Chlorobaculum tepidum, a green sulfur bacterium, utilizes chlorobactene as its major carotenoid, and this organism also accumulates a reduced form of this monocyclic pigment, 1′,2′-dihydrochlorobactene. The protein catalyzing this reduction is th
Autor:
Mats Wikström, Oonagh Shannon, Christofer Karlsson, Inga-Maria Frick, Ariane Neumann, Lars Björck
Publikováno v:
The Journal of Biological Chemistry
Some strains of the bacterial pathogen Streptococcus pyogenes secrete protein SIC (streptococcal inhibitor of complement), including strains of the clinically relevant M1 serotype. SIC neutralizes the effect of a number of antimicrobial proteins/pept
Publikováno v:
J Biol Chem
A critical role of influenza A virus nonstructural protein 1 (NS1) is to antagonize the host cellular antiviral response. NS1 accomplishes this role through numerous interactions with host proteins, including the cytoplasmic pathogen recognition rece