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Publikováno v:
The Journal of antimicrobial chemotherapy. 67(10)
OBJECTIVES Recent work with the yeast model revealed that the antiprotozoal drug quinine competes with tryptophan for uptake via a common transport protein, causing cellular tryptophan starvation. In the present work, it was hypothesized that similar
Autor:
Hao-Chun Chang, Yu-Chung Chuang, Jann-Tay Wang, Yee-Chun Chen, Shan-Chwen Chang, Ching-Lan Lu
Publikováno v:
The Journal of antimicrobial chemotherapy. 67(9)
Objectives: Vancomycin-resistant enterococci (VRE), particularly vancomycin-resistant Enterococcus faecium (VREfm), have emerged among the leading pathogens causing hospital-acquired infections worldwide. We aimed to examine whether there were newly
Autor:
Barbara Del Pin, Federico Pea, Eleonora Zamparini, Pierluigi Viale, Piergiorgio Cojutti, Mario Furlanut
Publikováno v:
The Journal of antimicrobial chemotherapy. 67(8)
BJECTIVES: Prolonged treatment with linezolid may cause toxicity. The purpose of this study was to define pharmacodynamic thresholds for improving safety outcomes of linezolid. METHODS: We performed a retrospective study of patients who had trough (C
Autor:
Jan W. Mulder, Wiete Kromdijk, Hilde Rosing, Alwin D. R. Huitema, Patrick M. Smit, Jos H. Beijnen
Publikováno v:
The Journal of antimicrobial chemotherapy. 67(5)
Plasma concentrations are frequently used for therapeutic drug monitoring of antiretroviral drugs. Dried blood spot sampling offers a patient-friendly and easy alternative to plasma sampling. However, dried blood spot concentrations are not necessari
Autor:
Petra F. G. Wolffs, Rogier M. Hopstaken, M. den Heyer, Ellen E. Stobberingh, Cathrien A. Bruggeman, M. I. A. Rijnders
Publikováno v:
Journal of Antimicrobial Chemotherapy, 67(5), 1167-1180. Oxford University Press
We evaluated the susceptibility to fusidic acid, mupirocin and retapamulin of Staphylococcus aureus isolated from nasal and wound swabs. The susceptibility to the three agents of S. aureus isolated from general patients in the south of The Netherland
Autor:
Lorenzo Minoli, M. Stoll, M. Storgaard, Sorin Rugină, R. Greil, J. Hernandez Quero, Y van Delft, Andrew Hill, E. Voronin, Dan Turner, Philippe Morlat, N. Vetter, S. Maayan, Claudine Duvivier, Gerd Fätkenheuer, Andrea Antinori, J. Durant, Gaetano Filice, Stephan Marks, B. Gruzdev, A. Pronin, W. Schmidt, C. Stellbrink, Mark T. Nelson, Court Pedersen, Daniel Podzamczer, A. Streinu, Albrecht Stoehr, Gatell Jm, Armin Rieger, C. Miralles Alvarez, Chloe Orkin, G. Di Perri, L. Itzchak, B Clotet, Dénes Bánhegyi, D. Duiculescu, E. Shahar, Margaret A. Johnson, Adriano Lazzarin, M. Andreoni, Christine Katlama, Juergen K. Rockstroh, M Fisher, David Rey, G. Carosi, Pere Domingo, S. Erscoiu, C. Duvvier, Vadim Pokrovsky, Julie Fox, Christoph Stephan, A. Yakovlev, J. Feher, Stefan Esser, L. Cotte, Jose R. Arribas, Hansjakob Furrer
Publikováno v:
Fätkenheuer, G, Duvivier, C, Rieger, A, Durant, J, Rey, D, Schmidt, W, Hill, A, van Delft, Y, Marks, S, SENSE Study Team & Pedersen, C 2012, ' Lipid profiles for etravirine versus efavirenz in treatment-naive patients in the randomized, double-blind SENSE trial ', Journal of Antimicrobial Chemotherapy, vol. 67, no. 3, pp. 685-90 . https://doi.org/10.1093/jac/dkr533
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Background: Etravirine is approved for use in treatment-experienced patients at a dose of 200 mg twice daily. Efavirenz has been associated with greater increases in serum lipids compared with other non-nucleosides in randomized trials of first-line
Autor:
Linda Tristani, Hillary VanDeWall, Benjamin Woo, Thomas P. Lodise, Antonio Rivera, Amanda Dihmess, Nimish Patel, Hsin K. Li, Raymond P. Smith
Publikováno v:
The Journal of antimicrobial chemotherapy. 67(3)
Objectives The primary objectives were to compare the incidences of severe thrombocytopenia, critical thrombocytopenia and a relative decline in platelets from baseline (≥50% decline) between patients receiving linezolid and those receiving vancomy
Autor:
Ashini Jayasuriya, Erasmus Smit, Andrew Owen, David Back, Sris Allan, Stephen Taylor, Ed Wilkins, Lisa Heald, Gerry Gilleran, Martin Fisher, Sarah Fidler
Publikováno v:
The Journal of antimicrobial chemotherapy. 67(3)
We designed two different studies to evaluate two different combination antiretroviral therapy (cART) stopping strategies namely a 'staggered stop' approach (STOP 1 study) and a 'protected stop' approach (STOP 2 study) to find the best 'universal sto
Autor:
Shanmei Liao, Donnie McGrath, Xiaohui Xu, Jenny Zhang, Li Zhu, Jean-Michel Molina, Awny Farajallah, Richard Bertz, Timothy Eley, Mark Krystal, Michael Child, Anna Persson, Heather Sevinsky
Publikováno v:
The Journal of antimicrobial chemotherapy. 67(2)
Objectives To characterize the pharmacokinetics and inhibitory quotient (IQ) of atazanavir/ritonavir- and lopinavir/ritonavir-based regimens in HIV-infected, treatment-naive patients. Methods The CASTLE Study was a 96 week randomized study comparing
Autor:
Ronald Anderson, Ndiafhi Daphney Mutepe, Guy A. Richards, Riana Cockeran, Annette J. Theron, Gregory Ronald Tintinger, Paraskevi Irene Stivaktas, Charles Feldman, Helen C. Steel
Publikováno v:
The Journal of antimicrobial chemotherapy. 67(1)
Tigecycline is the prototype of the recently introduced, intravenously administered glycylcycline class of antibiotics, developed in response to the increasing problem of antibiotic resistance in Gram-positive bacteria, especially Staphylococcus aure