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of 140
pro vyhledávání: ''
Autor:
Wairimu Chege, Craig W. Hendrix, Roy M. Gulick, Krista Yuhas, Kenneth H. Mayer, Ying Q. Chen, Karen L. Klingman, Marybeth McCauley, Raphael J. Landovitz, Todd T. Brown, Mark A. Marzinke, Timothy J. Wilkin
Publikováno v:
The Journal of antimicrobial chemotherapy, vol 77, iss 2
Background Tenofovir disoproxil fumarate-containing pre-exposure prophylaxis (PrEP) has been associated with decreases in bone mineral density (BMD), but the bone effects of other non-tenofovir disoproxil fumarate candidate PrEP regimens are not well
Autor:
Majid Hajizadeh Farsani, Amir Hosein Jafari Kashi, Sara Mobarak, Shokrollah Salmanzadeh, Bryony Simmons, Hani Esmaeilian, Andrew Hill, Zahra Lotfi, Morteza Mobarak, Sajedeh Mousaviasl, Ramin Tabibi, Saeid Bitaraf, Gholamali Eslami, Aseni Wickramatillake, Hannah Wentzel, Anahita Sadeghi, Esmat Radmanesh, Seyed Mehdi Talebzadeh, Sedigheh Marjani, Saeed Jelvay, Mahboobeh Momtazan, James Freeman
Publikováno v:
Journal of Antimicrobial Chemotherapy
Objectives Sofosbuvir and daclatasvir are direct-acting antivirals highly effective against hepatitis C virus. There is some in silico and in vitro evidence that suggests these agents may also be effective against SARS-CoV-2. This trial evaluated the
Autor:
Fabienne Caby, Anne-Geneviève Marcelin, Helga Junot, Cathia Soulié, Marc-Antoine Valantin, Marc Wirden, Roland Tubiana, Lise Durand, Patrick Tilleul, Christine Katlama, Lambert Assoumou, Gilles Peytavin, Myriam Kirstetter, Thi Thu-Thuy Nguyen
Publikováno v:
The Journal of antimicrobial chemotherapy. 74(9)
Objectives In a context of life-long therapy, we asked whether it could be possible to reduce the number of antiretroviral drugs without jeopardizing viral suppression. Methods ECOVIR was a prospective study aiming to assess whether in patients on co
Autor:
Keisha Alexander, Joshua Blum, Peter L. Anderson, Samantha MaWhinney, Lucas Ellison, Becky Jo Kerr, Ryan Huntley, Jose R Castillo-Mancilla, Christine E. MacBrayne, Lane R. Bushman, Kristina M Brooks, Jennifer J. Kiser
Publikováno v:
J Antimicrob Chemother
BackgroundIntracellular tenofovir diphosphate concentrations are markedly increased in HIV/HCV coinfected individuals receiving tenofovir disoproxil fumarate (TDF) with sofosbuvir-containing treatment. Sofosbuvir may inhibit the hydrolysis of TDF to
Autor:
Giulia Spoletini, N. Shaw, Miles Denton, Daniel Peckham, Paul Whitaker, Christine Etherington, Ian Clifton
Publikováno v:
The Journal of antimicrobial chemotherapy. 74(5)
Background The efficacy of antibiotic treatment in pulmonary and systemic infections in cystic fibrosis (CF) is limited by the increased prevalence of MDR strains of Pseudomonas aeruginosa and Burkholderia cepacia complex. Ceftazidime/avibactam is a
Autor:
Antonella d'Arminio Monforte, Alessandro, Cozzi-Lepri, DI BIAGIO, Antonio, Giulia, Marchetti, Sergio Lo Caputo, Stefano, Rusconi, Nicola, Gianotti, Valentina, Mazzotta, Giovanni, Mazzarello, Andrea, Costantini, Antonella, Castagna, Andrea, Antinori, A d'Arminio Monforte, Antinori, A, Andreoni, M, Castagna, A, Castelli, F, Cauda, R, G Di Perri, Galli, M, Iardino, R, Ippolito, G, Lazzarin, A, C Marchetti, G, Rezza, G, F von Schloesser, Viale, P, Ceccherini-Silberstein, F, Cozzi-Lepri, A, Girardi, E, S Lo Caputo, Mussini, C, Puoti, M, F Perno, C, Balotta, C, Bandera, A, Bonora, S, Borderi, M, Calcagno, A, Capetti, A, R Capobianchi, M, Cicalini, S, Cingolani, A, Cinque, P, A De Luca, A Di Biagio, Gianotti, N, Gori, A, Guaraldi, G, Lapadula, G, Lichtner, M, Madeddu, G, Maggiolo, F, Marchetti, G, Monno, L, Nozza, S, Pinnetti, C, E Quiros Roldan, Rossotti, R, Rusconi, S, M Santoro, M, Saracino, A, Sarmati, L, Fanti, I, Galli, L, Lorenzini, P, Rodan(`(o))', A, Macchia, M, Tavelli, A, Carletti, F, Carrara, S, A Di Caro, Graziano, S, Petrone, F, Prota, G, Quartu, S, Truffa, S, Giacometti, A, Costantini, A, Barocci, V, Angarano, G, Fabrizio, C, Suardi, C, Donati, V, Verucchi, G, Castelnuovo, F, Minardi, C, Menzaghi, B, Abeli, C, Cacopardo, B, Celesia, B, Vecchiet, J, Falasca, K, Pan, A, Lorenzotti, S, Sighinolfi, L, Segala, D, Blanc, P, Vichi, F, Cassola, G, Viscoli, C, Alessandrini, A, Bobbio, N, Mazzarello, G, Pozzetto, I, Bonfanti, P, Molteni, C, Chiodera, A, Milini, P, Nunnari, G, Pellican(`(o)), G, Rizzardini, G, Bai, F, C Moioli, M, Piolini, R, L Ridolfo, A, Salpietro, S, Tincati, C, Puzzolante, C, Migliorino, C, Sangiovanni, V, Borgia, G, Esposito, V, F Di Martino, Gentile, I, Maddaloni, L, M Cattelan, A, Marinello, S, Cascio, A, Colomba, C, Baldelli, F, Schiaroli, E, Parruti, G, Sozio, F, Magnani, G, A Ursitti, M, Cristaudo, A, Vullo, V, Acinapura, R, Baldin, G, Capozzi, M, Mondi, A, M Rivano Capparucia, Iaiani, G, Latini, A, Gagliardini, R, M Plazzi, M, Savinelli, S, Vergori, A, Cecchetto, M, Viviani, F, Bagella, P, Rossetti, B, Franco, A, R Fontana Del Vecchio, Francisci, D, C Di Giuli, Caramello, P, C Orofino, G, Sciandra, M, Bassetti, M, Londero, A, Pellizzer, G, Manfrin, V, Starnini, G, A Ialungo and
Publikováno v:
The Journal of antimicrobial chemotherapy. 74(5)
Objectives To evaluate the durability of three integrase strand transfer inhibitors (INSTIs) and two NRTIs in ART-naive individuals. Methods The study design was observational. Patients were HIV-positive, ART-naive subjects starting raltegravir, elvi
Autor:
Manuela Colafigli, S La Monica, Antonio D'Avolio, Jessica Cusato, Alberto Borghetti, A. De Luca, Enrica Tamburrini, Simone Belmonti, Francesca Lombardi, Elena Visconti, V. Delle Donne, S Di Giambenedetto, Stefano Bonora, R. De Marco, Nicoletta Ciccarelli, G. Di Perri, Andrea Calcagno
Publikováno v:
The Journal of antimicrobial chemotherapy. 74(4)
Background Neuropsychiatric symptoms (NPs) have been reported with dolutegravir use. We hypothesized that increasing dolutegravir trough concentrations (Ctrough) and/or polymorphism in the SLC22A2 gene, encoding the organic cation transporter-2 (OCT2
Autor:
Véronique, Joly, Charles, Burdet, Roland, Landman, Marie, Vigan, Charlotte, Charpentier, Christine, Katlama, André, Cabié, Aida, Benalycherif, Gilles, Peytavin, Patrick, Yeni, France, Mentre, Anne-Laure, Argoud, Imane, Amri, Diane, Descamps, Yazdan, Yazdanpanah, Babacar, Sylla
Publikováno v:
Journal of Antimicrobial Chemotherapy
Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2019, 74 (3), pp.739-745. ⟨10.1093/jac/dky467⟩
Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2019, 74 (3), pp.739-745. ⟨10.1093/jac/dky467⟩
International audience; OBJECTIVES:To evaluate the dolutegravir+lamivudine combination in virologically suppressed patients living with HIV.METHODS:The ANRS 167 LAMIDOL trial was an open-label, single arm, multicentre trial assessing once-daily dolut
Publikováno v:
The Journal of antimicrobial chemotherapy. 73(11)
Background Vancomycin remains the mainstay of empirical therapy directed against MRSA. National guidelines recommend empirical dosing based on total body weight with trough-level therapeutic drug monitoring (TDM), which may not be optimal in obese an
Autor:
Bruno Ledergerber, Andrew Kambugu, Andrea Calcagno, Allan Buzibye, Jessica Cusato, Amrei von Braun, Jan Fehr, Christine Sekaggya-Wiltshire, Barbara Castelnuovo, Mohammed Lamorde
Publikováno v:
The Journal of antimicrobial chemotherapy. 74(1)
Objectives To report the efavirenz serum concentrations in TB/HIV-coinfected Ugandan adults on concomitant anti-TB treatment and analyse factors associated with elevated concentrations in this specific population. Methods Serum efavirenz concentratio