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Publikováno v:
The International Journal of Biological Markers. 18:106-115
The present study on the prognostic and predictive value of serine proteases was conducted in 460 early breast cancer patients mostly treated with some kind of adjuvant systemic therapy: 156 received chemotherapy, 141 hormone therapy and 111 a combin
Publikováno v:
The International Journal of Biological Markers. 18:152-155
Abnormally high blood levels of vascular endothelial growth factor (VEGF) appear to be associated with a poor prognosis in advanced cancer, probably as a consequence of its angiogenic and immunosuppressive effects. The prognostic significance of chan
Publikováno v:
The International journal of biological markers. 30(1)
Background Early detection of colorectal cancer (CRC) is crucial to reducing tumor-related mortality. Evaluating aberrantly methylated DNA in stool is promising for CRC screening. However, DNA methylation in the colonic epithelium of background mucos
Autor:
E Fugamalli, Paolo Lissoni, A Ardizzoia, Tancini G, S Secondino, Gianstefano Gardani, F Malugani
Publikováno v:
The International Journal of Biological Markers. 15:308-311
Angiogenesis is essential for tumor growth. Since vascular endothelial growth factor (VEGF) represents the main angiogenic factor, the control of VEGF secretion could constitute the most important mechanism to achieve the inhibition of angiogenesis-r
Publikováno v:
The International Journal of Biological Markers. 13:92-97
Polyamines (putrescine, spermidine and spermine) are essential for the proliferation of normal and neoplastic cells, and have been repeatedly recommended as tumor markers, with contrasting and elusive results. In the present study the urinary excreti
Autor:
G N Raval, Balar Db, L. J. Parekh, Prabhudas S. Patel, Rakesh Rawal, M.M. Patel, Devendra D. Patel
Publikováno v:
The International Journal of Biological Markers. 12:61-67
Serum levels of sialic acid and alkaline DNase (ADA) were analysed in 495 blood samples collected from 170 breast cancer patients before and during/after anticancer treatment. Fifty-six healthy females were included in the study to define the cutoff
Autor:
Marco Merlano, Mauro Feola, Cristiana Lo Nigro, Ornella Garrone, Daniela Vivenza, Martino Monteverde
Publikováno v:
The International journal of biological markers. 28(4)
Background Anthracyclines are among the most active drugs against breast cancer, but can exert cardiotoxic effects eventually resulting in congestive heart failure (CHF). Identifying breast cancer patients at high risk of developing cardiotoxicity af
Publikováno v:
The International journal of biological markers. 28(1)
Background The prognostic significance of immunocytochemical analysis of tumour vascular endothelial growth factor (VEGF) and its 2 receptors, VEGF-R1 and VEGF-R2, remains incompletely investigated in patients with oesophagogastric cancer. Methods Pa
Autor:
A. Ruibal Morell, M.T. Allende Monclus, J.M. García García, M.A. Martínez Muñiz, J.R. Hernández Hernández
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
Various authors have proposed the use of hyaluronic acid (HA) as a tumor marker. In order to analyze its usefulness as a marker in bronchogenic carcinoma, the most common carcinoma in men, we determined the HA values in serum and bronchoalveolar lava
Autor:
Peracchia A, Giuliano Sansebastiano, Leopoldo Sarli, Nicola Pietra, M. Fontanesi, G. Saccani Jotti, N. Orsi, Gabriella Becchi
Publikováno v:
The International Journal of Biological Markers. 10:11-16
DNA content was determined by flow cytometry in a series of 51 paired fresh tissue samples of primary colorectal carcinomas and the respective non-neoplastic adjacent mucosa in order to assess the relationship between DNA ploidy and the most commonly