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Autor:
Yinxing Zhu, Dongying Gu, Manman Chen, Yang Gong, Nan Chen, Xuedan Zhu, Xiaowen Cui, Han Yang, Xinying Huo, Jiali Dai, Cuiju Tang, Huanhuan Huang
Publikováno v:
The International Journal of Biological Markers. 36:28-35
Background: Circulating tumor cells and serum tumor markers have been found significant in predicting outcome for several malignancies. However, their role in gastric cancer is not fully clarified. We conducted a retrospective study to explore the pr
Publikováno v:
The International Journal of Biological Markers. 35:44-50
Background: To understand the association between driver gene variations and age and gender in patients with lung adenocarcinoma, we investigated mutations of the three most important driver genes—epidermal growth factor receptor (EGFR), anaplastic
Autor:
Cristian Mauro, Lorenzo Spaggiari, Rita Passerini, Domenico Galetta, M Teresa Sandri, Paola Lentati, Davide Radice
Publikováno v:
The International Journal of Biological Markers. 34:163-167
Background: Testing for circulating biomarkers in lung cancer is hampered by the insufficient specificity. We aimed to assess the relative diagnostic accuracy of pro-gastrin-releasing peptide (ProGRP) for the differential diagnosis of small cell lung
Autor:
Jung-Soo Pyo, Young San Ko
Publikováno v:
The International Journal of Biological Markers. 34:132-138
Purpose: This study aimed to elucidate the clinicopathological significance and prognostic role of tumor-infiltrating lymphocytes in colorectal cancer. Methods: The immunohistochemistry of CD3 and CD8 was performed on 265 human colorectal cancer tiss
Autor:
Christina Bellinger, Linda J. Metheny-Barlow, Jimmy Ruiz, Lance D. Miller, Boris Pasche, Stacey S O'Neill, W. Jeffrey Petty, James M. Taylor, Kounosuke Watabe, Emory R. McTyre, Jing Su, Fei Xing, Michael D. Chan, Hui-Wen Lo, Travis Dotson, Ammoren E. Dohm
Publikováno v:
The International journal of biological markers
Purpose/Objectives: We aimed to assess the predictive value of a lung cancer gene panel for the development of brain metastases. Materials/Methods: Between 2011 and 2015, 102 patients with lung cancer were prospectively enrolled in a clinical trial i
Autor:
Jeng Kai Jiang, Wei Shone Chen, Chia Chu Chang, Shih Ching Chang, Shung Haur Yang, Yuan Tzu Lan, Jen Kou Lin, Chun Chi Lin, Hung Hsin Lin, Tzu Chen Lin, Huann Sheng Wang
Publikováno v:
The International Journal of Biological Markers. 30:88-95
Purpose This study aimed to determine the prognostic value of mutations in the tumor suppressor gene FBXW7 for clinical outcomes in colorectal cancer (CRC). Methods Between January 2000 and December 2009, FBXW7 mutations in tumor tissues from 1,519 C
Autor:
Konstantinos I. Gourgoulianis, Apostolos Zaravinos, Zoe Daniil, Demetrios A. Spandidos, Sotirios G. Doukas, Dimitra P. Vageli, George K. Koukoulis, Jubrail Dahabreh
Publikováno v:
The International Journal of Biological Markers. 27:400-404
Background We recently showed that the mRNA levels of mismatch repair (MMR) proteins in non-small cell lung carcinoma (NSCLC) tissue specimens and the phenotypic translation of molecular MMR data refines the biology of the MMR system with consequent
Autor:
Kyriaki Masselou, Nikolaos Kopanakis, Helias Margaris, George C. Zografos, George Vasiliades, Michalis Vasiloglou, Theodore Liakakos, Evniki Kokosi
Publikováno v:
The International Journal of Biological Markers. 27:186-194
Background Previous studies have demonstrated altered levels of hematopoietic cytokines in the serum of patients with different types of cancer. Methods We measured the serum levels of the hematopoietic cytokines stem cell factor (SCF), interleukin 3
Publikováno v:
The International Journal of Biological Markers. 27:118-124
This study aimed at assessing the role of monocyte chemoattractant protein-1 (MCP-1), tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in the control of pleural effusion (PE) and survival in patients with primary lung adenocarcinoma. The co
Publikováno v:
The International Journal of Biological Markers. 25:136-140
Pancreatic carcinoma is one of the most malignant and aggressive cancers. The identification of prognostic factors is thought to be useful in directing treatment. Transcription factor Jun dimerization protein 2 (JDP2), a member of the activator prote