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pro vyhledávání: '"Marios C Papadopoulos"'
Autor:
Marios C. Papadopoulos, Lukmanee Tradtrantip, Marc O. Anderson, Alan S. Verkman, Samira Saadoun, Puay-Wah Phuan, Jeffrey Bennett, Hua Zhang
Publikováno v:
The FASEB Journal. 26:2197-2208
Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of spinal cord and optic nerve caused by pathogenic autoantibodies (NMO-IgG) against astrocyte aquaporin-4 (AQP4). We developed a high-throughput screen to identify blockers of NMO-I
Publikováno v:
The FASEB Journal. 19:1-19
Diffusion of solutes and macromolecules in brain extracellular space (ECS) is important for normal brain function and efficient drug delivery, and is thought to be impaired in edematous brain. Here we measured the diffusion of an inert macromolecular