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Publikováno v:
The European journal of neuroscience. 9(10)
Control of extrasynaptic glutamate concentration in the central nervous system is an important determinant of neurotransmission and excitotoxicity. Mechanisms that modulate glutamate transporter function are therefore critical factors in these proces
Autor:
Niels C. Danbolt, Kyrre Ullensvang, Giorgio Racagni, Barbara Lodi Rizzini, Andrea Volterra, Davide Trotti, Paola Bezzi
Publikováno v:
Scopus-Elsevier
We studied the early and late effects of L-trans-pyrrolidine-2,4-dicarboxylate (PDC), a competitive inhibitor of glutamate uptake with low affinity for glutamate receptors, in co-cultures of rat cortical neurons and glia expressing spontaneous excita