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Publikováno v:
The American journal of physiology. 277(6)
The developing lung contains surfactant protein (SP) C mRNA levels comparable to term values before mature type II cells and alveolar surfactant lipids are detectable. Estimates of the amount of mature SP-C in the alveolar lavages of preterm lungs ar
Autor:
Lilin Zhong, Carlota Sumbilla, Iain K. Farrance, Hailun Ma, Giuseppe Inesi, Marco Cavagna, David A. Lewis
Publikováno v:
The American journal of physiology. 277(6)
Cultured COS-1 cells, as well as chicken embryonic and neonatal rat cardiac myocytes, were infected with recombinant adenovirus vectors to define limiting factors in the expression and Ca2+transport function of recombinant sarcoplasmic-endoplasmic re
Publikováno v:
The American journal of physiology. 277(6)
The mammalian cell cytoskeleton consists of a diverse group of fibrillar elements that play a pivotal role in mediating a number of digestive and nondigestive cell functions, including secretion, absorption, motility, mechanical integrity, and mitosi
Autor:
Yih-Tai Chen, Sandra S. Shasby, Anant Kamath, D. Michael Shasby, Dana R. Ries, Michael C. Winter
Publikováno v:
The American journal of physiology. 277(5)
We tested the hypothesis that histamine alters the focal apposition of endothelial cells by acting on sites of cadherin-mediated cell-cell adhesion. Focal apposition was measured as the impedance of a cell-covered electrode, which was partitioned int
Autor:
Elizabeth O. Harrington, Nancy Parks, Anthony Smeglin, Laura L. Likar, Karen Heins, Sharon Rounds, K. Chul Kim
Publikováno v:
The American journal of physiology. 277(5)
Accumulation of intraluminal polymorphonuclear leukocytes (PMN) is a hallmark of inflammatory diseases of the airways. Extracellular nucleotides stimulate PMN adhesion to human main pulmonary artery endothelial cells (HPAEC) by a purinoceptor-mediate
Publikováno v:
The American journal of physiology. 277(5)
This study examined cross talk between phospholipase C-coupled muscarinic M3and bradykinin B2receptors coexpressed in Chinese hamster ovary (CHO) cells. Agonists of either receptor enhanced phosphoinositide signaling (which rapidly desensitized) and
Autor:
You Yang Zhao, David R. Pimental, Ragavendra R. Baliga, William W. Simmons, Mark A. Marchionni, Ralph A. Kelly, Douglas B. Sawyer
Publikováno v:
The American journal of physiology. 277(5)
Neuregulins are a family of growth-promoting peptides known to be important in neural and mesenchymal tissue development. Targeted disruption of neuregulin (NRG)-1 or one of two of its cognate receptors, ErbB2 or ErbB4, results in embryonic lethality
Publikováno v:
Europe PubMed Central
Transforming growth factor-alpha (TGF-alpha) is produced in the lung in experimental and human lung diseases; however, its physiological actions after lung injury are not understood. To determine the influence of TGF-alpha on acute lung injury, trans
Autor:
David A. Wink, Stefano Vicini, Muyiwa Gbadegesin, Sandra J. Hewett, Carol A. Colton, Ryszard M. Pluta, Michael Graham Espey
Publikováno v:
The American journal of physiology. 277(4)
Nitric oxide (NO) released from a new chemical class of donors enhances N-methyl-d-aspartate (NMDA) channel activity. Using whole cell and single-channel patch-clamp techniques, we have shown that ( Z)-1-[ N-(3-ammoniopropyl)- N-( n-propyl)amino]-NO
Autor:
Krishnamurthy Ramaswamy
Publikováno v:
The American journal of physiology. 277(4)
the water-soluble vitamins represent a structurally and functionally distinct set of organic compounds that are essential for human health. It has long been recognized that they play a vital role in intermediary metabolism, energy production, and cel