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of 3
pro vyhledávání: '"Franziska Theilig"'
Autor:
Franziska Theilig, Sebastian Bachmann, Robert Koesters, Danny Polzin, Anne Kathrin Enke, Brigitte Scolari
Publikováno v:
The American Journal of Pathology. 179:2177-2188
In many kidney diseases, the original insult primarily involves the glomerulus and may then pass onto the tubulointerstitium. Several hypotheses link glomerular disease to tubular injury; perhaps the foremost hypothesis involves chronic tubular hypox
Autor:
Franziska Theilig, Wilhelm Kriz, Robert Koesters, Michel LeHir, Hiltraud Hosser, Nicolas Picard, Rolf Gebhardt, Brigitte Kaissling, Adam B. Glick, Brunhilde Hähnel, Hermann Josef Gröne
Publikováno v:
The American Journal of Pathology. 177:632-643
We recently showed in a tetracycline-controlled transgenic mouse model that overexpression of transforming growth factor (TGF)-beta1 in renal tubules induces widespread peritubular fibrosis and focal degeneration of nephrons. In the present study we
Autor:
Milena Traykova-Brauch, Hermann Josef Gröne, Brunhilde Hähnel, Wilhelm Kriz, Hiltraud Hosser, Marcus J. Moeller, Brigitte Kaissling, Robert Koesters, Samy Hakroush, Franziska Theilig, Tjeerd P. Sijmonsma, Ann L. Akeson, Manfred Jugold
Publikováno v:
The American journal of pathology. 175(5)
The role of vascular endothelial growth factor (VEGF) in renal fibrosis, tubular cyst formation, and glomerular diseases is incompletely understood. We studied a new conditional transgenic mouse system [Pax8-rtTA/(tetO)(7)VEGF], which allows increase