Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Nakanishi A"'
Publikováno v:
Tetrahedron Letters. 54:5573-5576
As a result of difficulties in scaling up silicon-directed Nazarov cyclization for use in the synthesis of taxane natural products, the effect of additives was examined. Hydroxylic additives were found to convey a consistent beneficial effect on the
Publikováno v:
Tetrahedron Letters. 52:3090-3093
Acetogenins are valuable inhibitor probes to get an insight into the structural and functional properties of mitochondrial NADH-ubiquinone oxidoreductase (complex I). We synthesized a photoreactive acetogenin mimic ([125I]DANA) which retained a stron
Publikováno v:
Tetrahedron Letters. 54:4963-4965
A series of macrocyclic compounds, [6]cyclo-2,7-naphthylenes ([6]CNAP), composed of six naphthylene units are synthesized through a [3+3] convergent route in good to moderate yields. The synthesis method allowed for the introduction of dicarboxylic i
Autor:
Asao Nakamura, Haruhiro Okuda, Ikuo Nakanishi, Kazunori Anzai, Akiko Ohno, Naoki Miyata, Kiyoshi Fukuhara, Kohei Imai
Publikováno v:
Tetrahedron Letters. 50:6989-6992
The reaction of ninhydrin with (+)-catechin in the presence of TMSOTf resulted in condensation product 1, which consists of a 2:1 mixture of epimers at the C-2 position. The antioxidative radical-scavenging activity of 1 against the galvinoxyl radica
Publikováno v:
Tetrahedron Letters. 48:8526-8530
We show that the mono-N-methylated and -ethylated derivatives of the achiral compound bisguanidinobenzene undergo spontaneous asymmetric crystallization into a chiral form with chiral space group P212121. The absolute configurations of the chiral cry
Autor:
Ken Yamauchi, Toshihiro Nohara, Shin-ichi Ito, Tsuyoshi Ikeda, Hiroyuki Miyashita, Daisuke Nakano, Kenji Nakanishi
Publikováno v:
Tetrahedron Letters. 47:4355-4359
The aim of this study was to verify the antitumor role of the β- d -glucopyranosyl-(1→2)-O-[β- d -xylopyranosyl-(1→3)]-O-β- d -glucopyranosyl-(1→4)- d -galactopyranosyl (lycotetraosyl) moiety present in steroidal glycosides from Solanaceous
Publikováno v:
Tetrahedron Letters. 46:531-534
It has been found that NaBH 4 smoothly reduces the α-hydroxy-lactone moieties in ginkgolide and F-seco-ginkgolides to lactols. The reaction is rapid and stops at the lactol stage; the coordination of NaBH 4 to the conformationally rigid cage structu
Autor:
Shun-ichi Ikeda, Mayumi Yoshida, Fumito Koizumi, Rieko Tanaka, Hiroki Ishiguro, Satoshi Nakanishi, Shizuo Ohtaki, Yuichi Takahashi
Publikováno v:
Tetrahedron Letters. 45:7419-7422
EI-1941-1 ( 1a ) and EI-1941-2 ( 2a ) accompanied by EI-1941-3 ( 3 ) have been isolated from culture broth of Farrowia sp. E-1941 as the inhibitors of interleukin-1β converting enzyme. The structures of 1a , 2a , and 3 were elucidated by the analysi
Publikováno v:
Tetrahedron Letters. 44:583-586
Asymmetric synthesis of the two enantiomers of a small molecule thrombin inhibitor is described. The key step in the synthesis is the glucose-directed chiral induction in the hetero Diels–Alder cycloaddition step. Conformational analysis indicates
Publikováno v:
Tetrahedron Letters. 53:1180-1182
Iridium-catalyzed borylation of phenacenes with bis(pinacolato)diboron proceeds either in an edge-selective manner for diborylation or an edge/side-selective manner for tetraborylation. Multiply borylated [n]phenacenes (n = 3–5) were synthesized in