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Autor:
Hajime Saito, Yoshihiro Minamiya, Akiyuki Wakita, Souichi Koyota, Satoru Motoyama, Jiajia Liu, Yusuke Sato, Yuta Kawakita
Publikováno v:
Surgery Today. 47:1312-1320
To establish whether Sphingosine-1-phosphate (S1P) and sphingosine kinase 1 (SphK1) contribute to lymph node metastasis in esophageal squamous cell carcinoma.Immunohistochemical analysis of SphK1 expression was performed using a tissue microarray con
Autor:
Satoru Imura, Tetsuya Ikemoto, Shuichi Iwahashi, Yuji Morine, Mitsuo Shimada, Jun Hanaoka, Tohru Utsunomiya, Hiroki Mori
Publikováno v:
Surgery Today. 42:565-569
Thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) are important enzymes in the metabolism of 5-fluorouracil, which have been examined as possible predictive markers. We conducted this study to clarify the role of TS and DPD expressi
Autor:
Tetsuya Ikemoto, Satoru Imura, Tohru Utsunomiya, Hidenori Miyake, Jun Hanaka, Mami Kanamoto, Mitsuo Shimada, Yuji Morine, Nobuhiro Kurita
Publikováno v:
Surgery Today. 42:135-140
Thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) are important enzymes in the metabolism of 5-fluorouracil and possible predictive markers. We conducted this study to clarify if TS and DPD gene expressions are a prognostic indicato
Gastrointestinal stromal tumor with two genetic abnormalities on different alleles: Report of a case
Autor:
Shigeo Ohki, Naomi Matsumura, Takashi Ishikawa, Hideyuki Ike, Shingo Hasegawa, Shuuji Saito, Yasushi Ichikawa, Shoichi Fujii, Akira Nakano, Mitsuyoshi Ota, Yohei Miyagi, Shigeru Yamagishi, Chikara Kunizaki, Hiroshi Shimada
Publikováno v:
Surgery Today. 40:262-266
We report a case of a gastrointestinal stromal tumor (GIST) with strong and faint KIT protein staining, respectively, at two different sites. A single point mutation (c1727 T>C) was detected in DNA extracted from both sites, and a further deletion mu
Publikováno v:
Surgery Today. 28:367-372
We studied the role of angiogenesis in patients with medullary type poorly differentiated adenocarcinoma (MTPDA) of the stomach. Immunohistochemical analyses were conducted using antibodies against factor VIII (endothelial cells), vascular endothelia
Autor:
Hiroshi Izumi, Akio Yamazaki, Atsushi Morio, Hidehiro Konno, Hideaki Miyamoto, Toshiro Futagawa, Tsumin Oh
Publikováno v:
Surgery Today. 34
To determine if the preoperative administration of tegafur and uracil (UFT) to patients with lung adenocarcinoma could induce apoptosis.We conducted a randomized prospective study on 30 patients with lung adenocarcinoma, divided into two groups of 15