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Autor:
Johannes D. Clausen, Jens Peter Andersen, Maike Bublitz, Jesper V. Møller, Poul Nissen, Bertrand Arnou, Claus Olesen
Publikováno v:
Clausen, J D, Bublitz, M, Arnou, B J-P, Olesen, C, Andersen, J P, Møller, J V & Nissen, P 2016, ' Crystal Structure of the Vanadate-Inhibited Ca 2+-ATPase ', Structure, vol. 24, no. 4, pp. 617-623 . https://doi.org/10.1016/j.str.2016.02.018
Vanadate is the hallmark inhibitor of the P-type ATPase family; however, structural details of its inhibitory mechanism have remained unresolved. We have determined the crystal structure of sarcoplasmic reticulum Ca(2+)-ATPase with bound vanadate in