Zobrazeno 1 - 10
of 28
pro vyhledávání: ''
Autor:
Ute Bissels, Yeong-Hoon Choi, Stefan Wild, Hartmut Scheel, Andreas Bosio, Stefan Tomiuk, Aleksandra Mihailovic, Thomas Tuschl, Markus Hafner
Publikováno v:
Stem Cells (Dayton, Ohio)
MicroRNAs (miRNAs) have been shown to play an important role in hematopoiesis. To elucidate the role of miRNAs in the early steps of hematopoiesis, we directly compared donor-matched CD133+ cells with the more differentiated CD34+CD133− and CD34−
Autor:
Malgorzata Sekula, Marta Adamiak, Sylwia Bobis-Wozowicz, Miroslaw Bik-Multanowski, Sylwia Kedracka-Krok, Zbigniew Madeja, Ewa K. Zuba-Surma, Elzbieta Kamycka, Urszula Jankowska, Dariusz Boruczkowski, Katarzyna Kmiotek, Michal Sarna, Buddhadeb Dawn, Anna Madetko-Talowska, Jacek Kołcz
Publikováno v:
Stem cells (Dayton, Ohio). 33(9)
Microvesicles (MVs) are membrane-enclosed cytoplasmic fragments released by normal and activated cells that have been described as important mediators of cell-to-cell communication. Although the ability of human induced pluripotent stem cells (hiPSCs
Publikováno v:
Stem Cells, 30(10), 2128-2139. Wiley-Blackwell
Mutations in the gene encoding the methyl-CpG-binding protein MECP2 are the major cause of Rett syndrome, an autism spectrum disorder mainly affecting young females. MeCP2 is an abundant chromatin-associated protein, but how and when its absence begi
Autor:
Jing Tang, Juan Peng, Zuguo Liu, Yong-Xiang Zhao, Tao Tao, Tetsuya Kawakita, Yihui Mao, Gang Tan, Scheffer C.G. Tseng, Jing-Xiang Zhong, Yueping Zhou, Wei Li, Hua Wang
Publikováno v:
Stem cells (Dayton, Ohio). 27(10)
Importin13 (IPO13), the newest member of importin-β family discovered recently, is a unique nucleus-cytoplasm bidirectional transport receptor protein. In this study, IPO13 expression in human corneal tissue, limbal epithelial primary explant and cl
Autor:
Julien Gaillard, Christian Jorgensen, Pierre Charbord, Bruno Delorme, Charalampos Pontikoglou, Luc Sensebé, Alain Langonné, Thomas Häupl, Danièle Noël, Jochen Ringe
Publikováno v:
Stem cells (Dayton, Ohio). 27(5)
Lineage-priming is a molecular model of stem cell (SC) differentiation in which proliferating SCs express a subset of genes associated to the differentiation pathways to which they can commit. This concept has been developed for hematopoietic SCs, bu
Publikováno v:
Stem cells (Dayton, Ohio). 25(11)
Dopamine (DA) neurons derived from stem cells are a valuable source for cell replacement therapy in Parkinson disease, to study the molecular mechanisms of DA neuron development, and for screening pharmaceutical compounds that target DA disorders. Co
Autor:
Yung Kuei Soong, Hsin Shih Wang, Hsiu Huei Peng, Tzu Hao Wang, Kuang Den Chen, Li Wen Hsu, Yu-Jen Chang, Yao Lung Chang, Ming-Song Tsai, Shiaw-Min Hwang, An Shine Chao, Yun-Shien Lee, Kuan Der Lee, Chao Nin Wang, Shuenn Dyh Chang
Publikováno v:
Stem cells (Dayton, Ohio). 25(10)
Using high-density oligonucleotide microarrays and functional network analyses, we examined whether MSCs derived from four different origins exhibited unique gene expression profiles individually and then compared the gene expression profiles of all
Autor:
Chang-Ki Min, Il-Hoan Oh, Bin Cho, Joon-Sung Lee, Gyeongsin Park, Seung-Jip Yang, Young-Ju Kang, Tae-Yoon Kim
Publikováno v:
Stem cells (Dayton, Ohio). 25(7)
Self-renewal of hematopoietic stem cells (HSCs) is key to their reconstituting ability, but the factors regulating the process remain poorly understood. Here, we show that Interleukin-10 (IL-10), a pleiotropic immune modulating cytokine, can also pla
Autor:
Jorge Domenech, Nathalie Gallay, Alain Langonné, Pierre Charbord, Olivier Herault, Emeline Marais, Bruno Delorme, Adriana López Ponte
Publikováno v:
Stem cells (Dayton, Ohio). 25(7)
Adult bone marrow (BM)-derived stem cells, including hematopoietic stem cells (HSCs) and MSCs, represent an important source of cells for the repair of a number of damaged tissues. In contrast to HSCs, the soluble factors able to induce MSC migration
Autor:
Marisa Jaconi, Elisabetta Cerbai, Laura Sartiani, Francesca Stillitano, Alessandro Mugelli, Esther Bettiol
Publikováno v:
Stem Cells, Vol. 25, No 5 (2007) pp. 1136-1144
Cardiomyocytes derived from human embryonic stem cells constitute a promising cell source for the regeneration of damaged hearts. The assessment of their in vitro functional properties is mandatory to envisage appropriate cardiac cell-based therapies