Zobrazeno 1 - 10
of 41
pro vyhledávání: ''
Satellite cell activation and retention of muscle regenerative potential after long-term denervation
Autor:
Scott L. Hansen, Alvin Wong, Jason H. Pomerantz, David M. Young, Steven M. Garcia, Stanley Tamaki, Emilie Barruet, Katharine Striedinger
Publikováno v:
Stem Cells. 39:331-344
Irreversible denervation atrophy remains an unsolved clinical problem, and the role of skeletal muscle stem cell (MuSC, satellite cell) depletion in this process is unclear. We investigated the ability of MuSCs to regenerate muscle in the context of
Autor:
Bruno Manadas, Nuno Sousa, Jeffrey M. Gimble, Rita C. Assunção-Silva, Fábio G. Teixeira, António J. Salgado, Eduardo D. Gomes, Angelo C. Lepore, Sandra I. Anjo, Nuno A. Silva, Ana O. Pires, Sofia Silva Mendes, Hugo Leite-Almeida
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Patients suffering from spinal cord injury (SCI) still have a dismal prognosis. Despite all the efforts developed in this area, currently there are no effective treatments. Therefore, cell therapies have been proposed as a viable alternative to the c
Autor:
Teresa Nieto-Miguel, Sara Galindo, José M. Herreras, Marina López-Paniagua, Esther Rey, Ana de la Mata, María Plata-Cordero, Margarita Calonge
Publikováno v:
UVaDOC. Repositorio Documental de la Universidad de Valladolid
instname
instname
Producción Científica
Limbal stem cells are responsible for the continuous renewal of the corneal epithelium. The destruction or dysfunction of these stem cells or their niche induces limbal stem cell deficiency (LSCD) leading to visual loss,
Limbal stem cells are responsible for the continuous renewal of the corneal epithelium. The destruction or dysfunction of these stem cells or their niche induces limbal stem cell deficiency (LSCD) leading to visual loss,
Autor:
Chris E. Czisch, Alan R. Harvey, May H. Han, Seok Voon White, Giles W. Plant, Christine D. Plant
Publikováno v:
Stem Cells. 34:1812-1825
Cellular transplantation strategies utilizing intraspinal injection of mesenchymal progenitor cells (MPCs) have been reported as beneficial for spinal cord injuries. However, intraspinal injection is not only technically challenging, but requires inv
Autor:
Yoshiya Matsuzaka, Teiji Tominaga, Takahiro Morita, Cesario V. Borlongan, Hiroyuki Sakata, Shohei Wakao, Kuniyasu Niizuma, Yasumasa Kuroda, Hiroki Uchida, Hajime Mushiake, Mari Dezawa, Yoshihiro Kushida
Publikováno v:
Stem Cells. 34:160-173
Objective: Muse cells reside as pre-existing pluripotent-like stem cells within the fibroblasts, are nontumorigenic, exhibit differentiation capacity into triploblastic-lineage cells, and replenish lost cells when transplanted in injury models. Cell
Publikováno v:
Stem Cells. 32:3075-3087
Limited treatments are available for perinatal/neonatal stroke. Induced pluripotent stem cells (iPSCs) hold therapeutic promise for stroke treatment, but the benefits of iPSC transplantation in neonates are relatively unknown. We hypothesized that tr
Autor:
Paramjeet Dhadda, Aileen King, Nance Beyer Nardi, Claire E. Clarkin, Peter M. Jones, Caroline P.D. Wheeler-Jones, Pedro Cesar Chagastelles
Publikováno v:
Stem Cells. 31:547-559
Following islet transplantation, islet graft revascularization is compromised due to loss of endothelial cells (ECs) during islet culture. TGF-β signaling pathways are essential for vascular homeostasis but their importance for islet EC function is
Autor:
Naser Muja, Jeff W.M. Bulte, Piotr Walczak, Chulani Galpoththawela, Candace L. Kerr, Heechul Kim, Assaf A. Gilad
Publikováno v:
STEM CELLS. 30:2820-2829
Transplantation of embryonic stem cells and their neural derivatives can lead to amelioration of the disease symptoms of experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis (MS). Oligodendroglial progenitors (OPs),
Autor:
Kan Chiba, Fumio Ide, Kazuo Tsubota, Hidetoshi Sumimoto, Makoto Matsui, Rika Yasuhara, Masaichi Chang Il Lee, Kenji Mishima, Takashi Sakurai, Yutaka Kawakami, Yumi Matsuzaki, Yo Mabuchi, Tatsuaki Nishiyama, Junichi Tanaka, Yusuke Amano, Gou Yamamoto, Hiroyuki Yamada, Ichiro Saito, Hiroko Inoue
Publikováno v:
Stem Cells. 30:1925-1937
Stem cell-based therapy has been proposed as a promising strategy for regenerating tissues lost through incurable diseases. Side population (SP) cells have been identified as putative stem cells in various organs. To examine therapeutic potential of
Autor:
Yingli Fu, Piotr Walczak, Brian W. Simons, Kenyatta M. Cosby, Kathleen L. Gabrielson, Wesley D. Gilson, Lawrence V. Hofmann, Dorota A. Kedziorek, Jeff W.M. Bulte, Dara L. Kraitchman, Bernard Kohl, Brad P. Barnett
Publikováno v:
Stem Cells. 30:1286-1296
The therapeutic goal in peripheral arterial disease (PAD) patients is to restore blood flow to ischemic tissue. Stem cell transplantation offers a new avenue to enhance arteriogenesis and angiogenesis. Two major problems with cell therapies are poor