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Autor:
Hugh S. Taylor, Aya Tal, Demetra Hufnagel, Elham Neisani, Fei Li, Stephanie Gidicsin, Zhihao Wang, Graciela Krikun, Myles H. Alderman, Alexis Coolidge, Ramanaiah Mamillapalli
Publikováno v:
Stem Cells. 36:881-890
Endometriosis is ectopic growth of endometrial tissue traditionally thought to arise through retrograde menstruation. We aimed to determine if cells derived from endometriosis could enter vascular circulation and lead to hematogenous dissemination. E
Autor:
Aideen O’Doherty, Jana Pindjakova, Timothy O'Brien, J. Mary Murphy, Frank Barry, Eric Farrell, Fergal J. O'Brien, Aleksandra Leszczynska
Publikováno v:
Stem Cells, 34(4), 913-923. Wiley-Blackwell
The cellular and molecular basis of vascular calcification (VC) in atherosclerosis is not fully understood. Here, we investigate role of resident/circulating progenitor cells in VC and contribution of inflammatory plaque environment to this process.
Autor:
Zhongjie Sun, Jun Fan
Publikováno v:
Stem Cells. 34:1615-1625
Klotho was originally discovered as an aging-suppressor gene. The purpose of this study was to investigate whether secreted Klotho (SKL) affects the proliferation and differentiation of adipose-derived stem cells (ADSCs). RT-PCR and Western blot anal
Autor:
Alex Cordero, Eva M. Trinidad, William C. Dougall, Chetan Deshpande, Eva González-Suárez, Jordi Serra-Musach, Pasquale Pellegrini, Miguel Angel Pujana, Adrián Sanz-Moreno
Publikováno v:
Stem Cells. 34:1027-1039
Prolactin and progesterone both orchestrate the proliferation and differentiation of the mammary gland during gestation. Differentiation of milk secreting alveoli depends on the presence of prolactin receptor, the downstream Jak2-Stat5 pathway and th
Autor:
Yoshiya Matsuzaka, Teiji Tominaga, Takahiro Morita, Cesario V. Borlongan, Hiroyuki Sakata, Shohei Wakao, Kuniyasu Niizuma, Yasumasa Kuroda, Hiroki Uchida, Hajime Mushiake, Mari Dezawa, Yoshihiro Kushida
Publikováno v:
Stem Cells. 34:160-173
Objective: Muse cells reside as pre-existing pluripotent-like stem cells within the fibroblasts, are nontumorigenic, exhibit differentiation capacity into triploblastic-lineage cells, and replenish lost cells when transplanted in injury models. Cell
Autor:
Ruben Garcia-Martin, Maria F. Rubin de Celis, Grigori Enikolopov, Triantafyllos Chavakis, Dierk Wittig, Andreas Androutsellis-Theotokis, Richard Funk, Stefan R. Bornstein, Monika Ehrhart-Bornstein, Gabriela D. Valencia
Publikováno v:
Stem Cells. 33:2037-2051
The neural crest-derived adrenal medulla is closely related to the sympathetic nervous system; however, unlike neural tissue, it is characterized by high plasticity which suggests the involvement of stem cells. Here, we show that a defined pool of gl
Single Adult Kidney Stem/Progenitor Cells Reconstitute Three-Dimensional Nephron Structures In Vitro
Publikováno v:
Stem Cells. 33:774-784
The kidneys are formed during development from two distinct primordial tissues, the metanephric mesenchyme and the ureteric bud. The metanephric mesenchyme develops into the kidney nephron, the minimal functional unit of the kidney. A nephron consist
Autor:
Chai K. Lim, Christopher Vidal, Gustavo Duque, Brigitte Santner-Nanan, Helen J. Ball, Nicholas H. Hunt, Gilles J. Guillemin, Wei Li, Ralph Nanan
Publikováno v:
Stem Cells. 33:111-121
The mechanisms involved in the anabolic effect of interferon gamma (IFNγ) on bone have not been carefully examined. Using microarray expression analysis, we found that IFNγ upregulates a set of genes associated with a tryptophan degradation pathway
Publikováno v:
Stem Cells. 32:3075-3087
Limited treatments are available for perinatal/neonatal stroke. Induced pluripotent stem cells (iPSCs) hold therapeutic promise for stroke treatment, but the benefits of iPSC transplantation in neonates are relatively unknown. We hypothesized that tr
Autor:
Rainer Glass, Felipe de Almeida Sassi, Helmut Kettenmann, Susanne A. Wolf, Kristin Stock, Alexander Garthe
Publikováno v:
Stem cells 32(12), 3183-3195 (2014). doi:10.1002/stem.1805
The capsaicin receptor (TRPV1, transient receptor potential vanilloid type 1) was first discovered in the peripheral nervous system as a detector of noxious chemical and thermal stimuli including the irritant chili pepper. Recently, there has been in