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Autor:
Ponthip Pratumkaew, Sudjit Luanpitpong, Phatchanat Klaihmon, Chanchao Lorthongpanich, Chuti Laowtammathron, Sukanya Meesa, Wichuda Suksomboon, Surapol Issaragrisil
Publikováno v:
Stem cell research. 64
Human induced pluripotent stem cell (iPSC) line MUSIi020-A was generated from T cells isolated from peripheral blood of a healthy 37-year-old female and reprogrammed using episomal plasmid vectors. The established transgene-free MUSIi020-A, which ret
Autor:
Zheng Jiang, Xiao-Jing Gu, Wei-Ming Su, Qing-Qing Duan, Jun-Yu Lin, Bei Cao, Hui-Fang Shang, Yong-Ping Chen
Publikováno v:
Stem cell research. 64
CHCHD2 mutations have been reported to cause Parkinson's disease (PD) by a loss of function in mitochondria. Most reported mutations, however, were missense, which was not the perfect model for a study of haploinsufficiency. Here, a truncated mutatio
Publikováno v:
Stem cell research. 64
CD34+ cells were isolated from peripheral blood of a breast cancer patient. By the introduction of five integration-free episomal vectors, the CD34+ cells were successfully reprogrammed and resulted in four iPSC clones. Flow Cytometry, reverse transc
Publikováno v:
Stem cell research. 64
VPS13B deletion and 16p13.11 duplication are related to mental disorders, such as schizophrenia. However, how these variants affect human neurons and contribute to the development of mental disorders is yet to be elucidated. In this study, we generat
Autor:
Pauline Mencke, Ibrahim Boussaad, Gizem Önal, Anneke J.A. Kievit, Agnita J.W. Boon, Wim Mandemakers, Vincenzo Bonifati, Rejko Krüger
Publikováno v:
Stem Cell Research, 62:102792. Elsevier Inc.
Here, we describe an induced pluripotent stem cell (iPSC) line that was derived from fibroblasts obtained from a monogenic Parkinson's disease (PD) patient. The disease was caused by a c.634-636delGCC mutation in the PARK7 gene leading to p.158P dele
Publikováno v:
Stem cell research. 63
Here we report the generation of the first Emirati iPSC line in the United Arab Emirates and name it KUSTi001-A. CD34+ hematopoietic cells purified from peripheral blood of a 27-year-old healthy female donor were reprogrammed using Sendai vectors. Tw
Autor:
Zhanchi Zhang, Jingrui Liu, Jiamin Zhang, Xian Xian, Peipei Hao, Yingtong Zhai, Jingke Cheng, Fengming Yue, Feng Luan, Min Ma, Qian Ren
Publikováno v:
Stem cell research. 64
Peripheral blood mononuclear cells derived from a 35-year-old healthy male were reprogrammed into induced pluripotent stem cells (iPSCs). The iPSCs maintained a normal karyotype, expressed various pluripotency stem cell markers, and showed potential
Autor:
Johanna Lotila, Tanja Hyvärinen, Heli Skottman, Laura Airas, Susanna Narkilahti, Sanna Hagman
Publikováno v:
Stem cell research. 63
Multiple sclerosis (MS) is a complex autoimmune disease of the central nervous system where the main pathogenetic events include demyelination and axonal degeneration. Here, we generated a human induced pluripotent stem cell (hiPSC) line from periphe
Autor:
Julian Schröter, Hanna Syring, Gudrun Göhring, Stefan Kölker, Thomas Opladen, Georg F. Hoffmann, Steffen Syrbe, Sabine Jung-Klawitter
Publikováno v:
Stem cell research. 64
TUBB2A tubulinopathy is a rare neurodevelopmental disorder with developmental delay, epilepsy, and less frequent malformations of cortical development compared to other tubulinopathies. Peripheral blood mononuclear cells (PBMCs) from a male subject h
Autor:
Julian Schröter, Hanna Syring, Gudrun Göhring, Stefan Kölker, Thomas Opladen, Georg F. Hoffmann, Steffen Syrbe, Sabine Jung-Klawitter
Publikováno v:
Stem cell research. 62
Variants in different neuronal tubulin isotypes cause severe neurodevelopmental disorders with cerebral malformations accompanied by developmental delay, motor impairment, and epilepsy, known as tubulinopathies. Induced pluripotent stem cells were ge