Zobrazeno 1 - 6
of 6
pro vyhledávání: '"11"'
Autor:
Clement Soleilhavoup, Kieran Patrick, Ulrika Marklund, Emma Moles-Garcia, Lucie Combes-Soia, Peter Hohenstein, Rosa Peltrini, Marco Travaglio, Shahida Sheraz, Lia Panman, Pedro Garção, Tony Oosterveen, Valérie Labas
Publikováno v:
Stem Cell Reports
Stem Cell Reports, 16(11), 2718-2735. CELL PRESS
Stem Cell Reports, 16(11), 2718-2735. CELL PRESS
Summary In Parkinson’s disease (PD), substantia nigra (SN) dopaminergic (DA) neurons degenerate, while related ventral tegmental area (VTA) DA neurons remain relatively unaffected. Here, we present a methodology that directs the differentiation of
Autor:
Jagroop Dhaliwal, Yingben Xue, Jean-Claude Béïque, Diane C. Lagace, Anthony Carter, Timal S. Kannangara
Publikováno v:
Stem Cell Reports, Vol 11, Iss 6, Pp 1327-1336 (2018)
Stem Cell Reports
Stem Cell Reports
Summary Ischemic stroke enhances the proliferation of adult-generated precursor cells that ectopically migrate toward the infarct. Studies have correlated precursor cell proliferation and subsequent adult neurogenesis with enhanced stroke recovery, y
Autor:
Osahiko Tsuji, Morio Matsumoto, Toshiki Okubo, Masaya Nakamura, Jun Kohyama, Narihito Nagoshi, Shinsuke Shibata, Munehisa Shinozaki, Hideyuki Okano, Yoshitaka Kase
Publikováno v:
Stem Cell Reports, Vol 11, Iss 6, Pp 1416-1432 (2018)
Stem Cell Reports
Stem Cell Reports
Summary Treatment involving regenerative medicine for chronic spinal cord injury (SCI) is difficult due to phase-dependent changes in the intraspinal environment. We previously reported that treatment with a gamma-secretase inhibitor (GSI), which inh
Autor:
K. Miyazaki, Bahar D. Yilmaz, Serdar E. Bulun, John S. Coon, Matthew T. Dyson, Tetsuo Maruyama, Yuichi Furukawa
Publikováno v:
Stem Cell Reports, Vol 11, Iss 5, Pp 1136-1155 (2018)
Stem Cell Reports
Stem Cell Reports
Summary Defective endometrial stromal fibroblasts (EMSFs) contribute to uterine factor infertility, endometriosis, and endometrial cancer. Induced pluripotent stem cells (iPSCs) derived from skin or bone marrow biopsies provide a patient-specific sou
Autor:
Yan Li, Matthew S. Elitt, Zachary S. Nevin, Paul J. Tesar, Angela M. Lager, H. Elizabeth Shick, Chen Weng, Drew J. Adams, Mayur Madhavan, Tyler E. Miller, Kevin C. Allan, Lilianne Barbar, Fulai Jin, Daniel C. Factor, Baraa S. Nawash, Benjamin L.L. Clayton
Publikováno v:
Stem Cell Reports, Vol 11, Iss 3, Pp 711-726 (2018)
Summary: Pelizaeus-Merzbacher disease (PMD) is a fatal X-linked disorder caused by loss of myelinating oligodendrocytes and consequent hypomyelination. The underlying cellular and molecular dysfunctions are not fully defined, but therapeutic enhancem
Autor:
Jürgen Pollheimer, Gudrun Meinhardt, Sasha Mendjan, Thomas R Burkard, Paulina A. Latos, Magdalena Gamperl, Sandra Haider, Ulrich Kaindl, Viktoria Kunihs, Adolf Ellinger, Christian Fiala, Martin Knöfler, Leila Saleh
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 11, Iss 2, Pp 537-551 (2018)
Stem Cell Reports, Vol 11, Iss 2, Pp 537-551 (2018)
Summary Defective placentation is the underlying cause of various pregnancy complications, such as severe intrauterine growth restriction and preeclampsia. However, studies on human placental development are hampered by the lack of a self-renewing in