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Background Expression of transcription-factors as Slug and Sox9 was recently described to determine mammary stem-cell state. Sox10 was previously shown to be present also in breast cancer. Protein overexpression of Slug, Sox9 and Sox10 were associate
Publikováno v:
SpringerPlus
Purpose The purpose of this study was to evaluate the magnetic resonance imaging (MRI) features of breast cancer according to intrinsic subtypes and to investigate whether the MRI and immunohistochemical findings were related to neoadjuvant chemother
Publikováno v:
SpringerPlus
We report a case of synchronous locally advanced bilateral breast cancer with different pathological responses to neoadjuvant chemotherapy with different biological character. The patient had presented bilateral breast cancer: the left breast cancer
Autor:
Ningqi Hou, Blase N. Polite, Sumita S. Bhatta, Olufunmilayo I. Olopade, Zakiya N Moton, Dezheng Huo, Susan Hong, Gini F. Fleming
Publikováno v:
SpringerPlus
Background Studies have demonstrated lower rates of breast cancer survival for Black versus White women. Factors implicated include later stages at diagnosis, differences in tumor biology, and lower compliance rates to adjuvant hormone therapy (AHT)
Publikováno v:
SPRINGERPLUS
SpringerPlus
SpringerPlus
Bevacizumab, a humanized monoclonal antibody directed against vascular endothelial growth factor, is an effective and well-tolerated treatment option for patients with breast cancer. Bevacizumab has demonstrated a gain in progression-free survival an
Autor:
Maegan V. Prummel, Claire M. B. Holloway, Amalia Plotogea, Frances P. O'Malley, Nelson Chong, Lucia Mirea, Rene Shumak, Anna M. Chiarelli
Publikováno v:
SpringerPlus
Introduction Although prognostic differences between screen-detected, interval and symptomatic breast cancers are known, factors associated with wait times to diagnosis among these three groups have not been studied. Methods Of the 16,373 invasive br
Autor:
Alberto Luini, Claudia Sangalli, Gabriella Pravettoni, Paola Arnaboldi, Claudio Lucchiari, Luigi Santoro
Publikováno v:
SpringerPlus
It is a well-established multidisciplinary practice at the European Institute of Oncology, that nurses and physicians often report their difficulties to clinical psychologists regarding adherence to hospital scheduling and procedures, when faced with
Autor:
Gregory R. Pond, Huijun Zhao, Eitan Amir, Lisa Vandermeer, Christina L. Addison, Mark Clemons, Sasha Mazzarello, Robyn Goldstein
Publikováno v:
SpringerPlus
While de-escalation of bisphosphonates from 4 to 12-weekly dosing has been shown to be clinically non-inferior to standard dosing, there is evidence the de-escalation is associated with increased bone turnover biomarkers. Here we evaluated the effect
Autor:
Kazuaki Yoshikawa, Riruke Maruyama, Nobuko Yamamoto, Hajime Kitagaki, Takeshi Yoshizako, Masayuki Itakura
Publikováno v:
SpringerPlus
Purpose The purpose of this study was to assess indications for stereotactic vacuum-assisted breast biopsy (SVAB) evaluated by breast 3 T-magnetic resonance (3 T-MR) imaging in patients showing suspicious microcalcifications on mammography and negati
Autor:
Flavio Monteiro Ayres, Jacqueline Andréia Bernardes Leão Cordeiro, Meire Luzia Gonçalves, Vera Aparecida Saddi, Cesar Augusto Sam Tiago Vilanova-Costa, Sarah Moreira Borja, Antonio Márcio Teodoro Cordeiro Silva
Publikováno v:
SpringerPlus
This study was conducted in order to investigate the implications of the R72P polymorphism in the TP53 gene in breast cancer risk. The enlightenment of this matter might provide a piece of information about the potential implications of this polymorp