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Autor:
Masafumi Shimoda, Naofumi Kagara, Tomonori Tanei, Atsushi Shimomura, Yasuto Naoi, Saki Matsui, Kenzo Shimazu, Seung Jin Kim, Chieko Mishima, Shinzaburo Noguchi
Publikováno v:
SpringerPlus
The aim of the present study was to investigate the promoter methylation status of TRIM9 in breast cancer and to determine the presence of TRIM9-methylated circulating tumor DNA (ctDNA) in plasma. Bisulfite sequencing with a next generation sequencer
Autor:
Andre Kajdacsy-Balla, Ryan Deaton, Peter H. Gann, Debra A. Tonetti, Meghan K. Hayes, Szilard Asztalos, William McDonald, Elizabeth L. Wiley, Nilanjana Banerji, Seema A. Khan, Thao Pham, Rajyasree Emmadi
Publikováno v:
SpringerPlus
Breast cancer risk increases transiently in the period following pregnancy; pregnancy-associated breast cancers (PABC) are more aggressive than cases diagnosed in nulliparous women. We have previously reported that in the normal human breast pregnanc
Publikováno v:
SpringerPlus
Background Expression of transcription-factors as Slug and Sox9 was recently described to determine mammary stem-cell state. Sox10 was previously shown to be present also in breast cancer. Protein overexpression of Slug, Sox9 and Sox10 were associate
Publikováno v:
SpringerPlus
Purpose The purpose of this study was to evaluate the magnetic resonance imaging (MRI) features of breast cancer according to intrinsic subtypes and to investigate whether the MRI and immunohistochemical findings were related to neoadjuvant chemother
Autor:
Georg F. Weber, Franz Hartung
Publikováno v:
SpringerPlus
Purpose: Despite a sizeable and continuously growing literature on osteopontin and cancer the molecule has not yet found entry into clinical diagnostics. Our identification of spliced variants that are more specific for cancer than the full-length tr
Autor:
Guoxian Sun, Julia Wulfkuhle, Ricardo Moraes, Hui Liu, Rita Circo, Zhaomei Mu, Sandra V. Fernandez, François Bertucci, Xuejun Zhang, Massimo Cristofanilli, Khoi Chu, Fredika M. Robertson, Jianming Pei, Sanford H. Barsky, Zaiming Ye, Emanuel F. Petricoin, Ruggero DeMaria, Katherine Alpaugh, Kimberly M. Boley, Steven Van Laere
Publikováno v:
SpringerPlus
SpringerPlus, SpringerOpen, 2013, 2 (1), pp.497. ⟨10.1186/2193-1801-2-497⟩
SpringerPlus, SpringerOpen, 2013, 2 (1), pp.497. ⟨10.1186/2193-1801-2-497⟩
Although Inflammatory Breast Cancer (IBC) is recognized as the most metastatic variant of locally advanced breast cancer, the molecular basis for the distinct clinical presentation and accelerated program of metastasis of IBC is unknown. Reverse phas
Autor:
Amy E. Hanlon Newell, Megan L. Troxell, Edward J. Keenan, Zhi Hu, Susan B. Olson, Shiuh Wen Luoh, Paul T. Spellman, Betsy Ramsey, Koei Chin
Publikováno v:
SpringerPlus
Background Testing for human epidermal growth factor receptor-2 (HER-2) in breast cancer is performed by either immunohistochemistry (IHC) or in situ hybridization (ISH). The growth factor receptor-bound protein-7 (GRB7) gene is in close proximity to