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Autor:
Pamala A. Jacobson, David Potter, Daniel A. Duprez, Ryan Shanley, Douglas Yee, Anne H. Blaes, Todd E. DeFor, Tufia C. Haddad, Heather Beckwith, Kinjal Sanghavi
Publikováno v:
SpringerPlus
Purpose Doxorubicin (DOX) chemotherapy can cause cardiac complications. Angiotensin converting enzyme inhibitors (ACEI) may protect against these complications. We performed a pharmacokinetics (PK) study to determine whether DOX levels are altered in
Autor:
Benford Mafuvadze, Sandy Goyette, Salman M. Hyder, Matthew Cook, Yayun Liang, Cynthia Besch-Williford
Publikováno v:
SpringerPlus
Purpose Clinical trials and epidemiological evidence have shown that combined estrogen/progestin hormone replacement therapy, but not estrogen therapy alone, increases breast cancer risk in post-menopausal women. Previously we have shown that natural
Autor:
Gregory R. Pond, Huijun Zhao, Eitan Amir, Lisa Vandermeer, Christina L. Addison, Mark Clemons, Sasha Mazzarello, Robyn Goldstein
Publikováno v:
SpringerPlus
While de-escalation of bisphosphonates from 4 to 12-weekly dosing has been shown to be clinically non-inferior to standard dosing, there is evidence the de-escalation is associated with increased bone turnover biomarkers. Here we evaluated the effect
Autor:
Georg F. Weber, Franz Hartung
Publikováno v:
SpringerPlus
Purpose: Despite a sizeable and continuously growing literature on osteopontin and cancer the molecule has not yet found entry into clinical diagnostics. Our identification of spliced variants that are more specific for cancer than the full-length tr
Autor:
Amy E. Hanlon Newell, Megan L. Troxell, Edward J. Keenan, Zhi Hu, Susan B. Olson, Shiuh Wen Luoh, Paul T. Spellman, Betsy Ramsey, Koei Chin
Publikováno v:
SpringerPlus
Background Testing for human epidermal growth factor receptor-2 (HER-2) in breast cancer is performed by either immunohistochemistry (IHC) or in situ hybridization (ISH). The growth factor receptor-bound protein-7 (GRB7) gene is in close proximity to