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Autor:
Yuichi Kasai, Ryu Iida, Koichi Masuda, Ryo Morimoto, Atsumasa Uchida, Masayoshi Sato, Koji Akeda, Toshihiko Sakakibara
Publikováno v:
Spine. 34:470-478
Study design Immunohistochemical and biochemical analyses of proteinase-activated receptor-2 (PAR-2) in rat and human intervertebral discs (IVDs). Objectives To examine the expression and function of PAR-2 in rat IVD cells, and to determine if PAR-2
Autor:
E. Thonar, Tong-Chuan He, Howard S. An, D. Greg Anderson, Frank M. Phillips, Daniel Pietryla, Yejia Zhang
Publikováno v:
Spine. 32:2515-2520
STUDY DESIGN An in vitro biologic study comparing the effects of a series of bone morphogenetic proteins (BMPs) and Sox9 on the extracellular matrix accumulation by bovine anulus fibrosus (AF) cells. OBJECTIVE To compare the effects of adenoviral-med
Autor:
Kei Miyamoto, Howard S. An, Koichi Masuda, Gunnar Andersson, Eugene J.-M.A. Thonar, Yoshiyuki Imai
Publikováno v:
Spine. 32:1303-1309
Study Design. In vitro assessment of the effects of recombinant human osteogenic protein-1 (rhOP-1) on the proteoglycan metabolism of human intervertebral disc cells. Objectives. To determine whether rhOP-1 is effective in stimulating the cell prolif
Autor:
Tomomitsu Hotta, Tohru Iwashina, Joji Mochida, Takeshi Miyazaki, Daisuke Sakai, Yukihiro Yamamoto, Eiren Toh, Sadaki Inokuchi, Kiyoshi Ando
Publikováno v:
Spine. 29:1515-1523
Study design Establishment and characterization of a de novo cell line derived from human nucleus pulposus cells using a recombinant simian virus 40 (SV40) adenovirus vector. Objectives To assess the feasibility of human nucleus pulposus cell line pr
Autor:
John M. Wozney
Publikováno v:
Spine. 27:S2-S8
Study design A literature review was conducted. Objectives To review the discovery of the bone morphogenetic proteins and describe the bone morphogenetic protein products that will or may be available for clinical use. Summary of background data Bone