Zobrazeno 81 - 90
of 366
pro vyhledávání: '"Preclinical research"'
Autor:
Rebecca W. Olsen, Trine Staalsoe, Casper Hempel, Michael F. Ofori, Nanna Dalgaard, Lars Hviid, Srinidhi Sudharson, William van der Puije, Jørgen A. L. Kurtzhals, Christian W. Wang
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
van der Puije, W, Wang, C W, Sudharson, S, Hempel, C, Olsen, R W, Dalgaard, N, Ofori, M F, Hviid, L, Kurtzhals, J A L & Staalsoe, T 2020, ' In vitro selection for adhesion of Plasmodium falciparum-infected erythrocytes to ABO antigens does not affect PfEMP1 and RIFIN expression ', Scientific Reports, vol. 10, no. 1, pp. 12871 . https://doi.org/10.1038/s41598-020-69666-9
Scientific Reports
van der Puije, W, Wang, C W, Sudharson, S, Hempel, C, Olsen, R W, Dalgaard, N, Ofori, M F, Hviid, L, Kurtzhals, J A L & Staalsoe, T 2020, ' In vitro selection for adhesion of Plasmodium falciparum-infected erythrocytes to ABO antigens does not affect PfEMP1 and RIFIN expression ', Scientific Reports, vol. 10, no. 1, pp. 12871 . https://doi.org/10.1038/s41598-020-69666-9
Plasmodium falciparum causes the most severe form of malaria in humans. The adhesion of the infected erythrocytes (IEs) to endothelial receptors (sequestration) and to uninfected erythrocytes (rosetting) are considered major elements in the pathogene
Autor:
Parameth Thiennimitr, Siriporn C. Chattipakorn, Arintaya Phrommintikul, Montree Wutthi-in, Nipon Chattipakorn, Supapon Cheevadhanarak, Weerayuth Kittichotirat, Sasiwan Kerdphoo, Sakawdaurn Yasom
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Metabolic syndrome (MetS) has become a worldwide health issue. Recent studies reveal that the human gut microbiota exerts a significant role in the pathogenesis of this disease. While drug treatments may greatly improve metabolic symptoms, little is
Autor:
Timir Datta-Chaudhuri, Marina Cracchiolo, Loren Rieth, Maria F. Lopez, Umair Ahmed, Yao-Chuan Chang, Theodoros P. Zanos, Jacquelyn N. Tomaio, Yousef Al-Abed, Stavros Zanos
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
Vagus nerve stimulation (VNS) is a bioelectronic therapy for disorders of the brain and peripheral organs, and a tool to study the physiology of autonomic circuits. Selective activation of afferent or efferent vagal fibers can maximize efficacy and m
Autor:
H. Brent Clark, Rajagopal N. Aravalli, John W. Osborn, Parker O’Brien, Dalong Liu, Hasan Aldiabat, Dusty Van Helden, M. Gerard O'Sullivan, Emad S. Ebbini, Alexandru Flaviu Tăbăran
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Carotid bodies (CBs) are chemoreceptors that monitor and register changes in the blood, including the levels of oxygen, carbon dioxide, and pH, and regulate breathing. Enhanced activity of CBs was shown to correlate with a significant elevation in th
Autor:
Claudia Fortes, Theres Meili, Regina Hofmann-Lehmann, Barbara Riond, Jasmin Walter, Jonas Grossmann, Ulrich Bleul, C Monthoux, Hanspeter Naegeli, Bernd Roschitzki
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, 10 (1)
Scientific Reports
Scientific Reports, 10 (1)
Scientific Reports
In vitro maturation (IVM) of oocytes has still a negative impact on the developmental competence of oocytes. Therefore, this study analysed the cumulus proteome of individual cumulus-oocyte complexes (COCs) with and without maturational competence, m
Autor:
Adina Boldeiu, Carsten Herskind, Mihaela Temelie, Roxana Cristina Popescu, D. A. Iancu, Frederik Wenz, Diana Savu, Frank A. Giordano, Hiltraud Hosser, I. Dorobantu, Bogdan Stefan Vasile, M. Straticiuc, Marlon R. Veldwijk, Ecaterina Andronescu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
The purpose of this study was to construct and characterize iron oxide nanoparticles (IONPCO) for intracellular delivery of the anthracycline doxorubicin (DOX; IONPDOX) in order to induce tumor cell inactivation. More than 80% of the loaded drug was
Autor:
Eun Jeong Go, Seon Ae Kim, Yoo Joon Sur, Mi-La Cho, Yun Hwan Kim, Asode Ananthram Shetty, Seok Jung Kim
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Scientific Reports
Scientific Reports
Effective engineering approaches for cartilage regeneration involve a combination of cells and biomaterial scaffolds. Multipotent mesenchymal stem cells (MSCs) are important sources for cartilage regeneration. Atelocollagen provides a suitable substr
Autor:
Marek Pieczka, Mohamed Arafkas, Alessio Pigazzi, Tanja Khosrawipour, Alice Martino, Sören Reinhard, Veria Khosrawipour, Jacek Bania, Justyna Schubert
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Scientific Reports
Scientific Reports
For decades, intraperitoneal chemotherapy (IPC) was delivered into the abdominal cavity as a liquid solution. This preliminary study aims to evaluate foam as a potential new drug carrier for IPC delivery. Foam-based intraperitoneal chemotherapy (FBIC
Autor:
Mithun Santra, Deeksha Katoch, Manni Luthra-Guptasarma, Maryada Sharma, Sahil Jain, Uma Nahar Saikia, Mangat R Dogra
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Induction of posterior vitreous detachment (PVD) by pharmacologic vitreolysis has been largely attempted through the use of enzymatic reagents. Ocriplasmin has been the only FDA-approved clinical reagent so far. Several adverse effects of ocriplasmin
Autor:
Sascha Halvachizadeh, Volkmar Falk, Thea Fleischmann, Miriam Lipiski, Francesco Maisano, Beate Kolb, Matthias Eberhard, Mareike Sauer, Nikola Cesarovic, Maximilian Y. Emmert, Hatem Alkadhi
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, 10 (1)
Scientific Reports
Scientific Reports, 10 (1)
Scientific Reports
The pig (Sus Scrofa Domestica) is an accepted model for preclinical evaluation of prosthetic heart valves and trans-catheter implantation techniques. Understanding porcine cardiac dimensions through three-dimensional computed tomography (CT), increas