Zobrazeno 1 - 10
of 81
pro vyhledávání: '"11"'
Autor:
Jitske Jansen, Marinka Bakker-van Bebber, Fieke Mooren, Markus A. Loeven, Brigith Willemsen, Jennifer Eymael, Catherine Meyer-Schwesinger, Bart Smeets, Shagun Sharma, Jack F.M. Wetzels, Henry B.P.M. Dijkman, Johan van der Vlag, Laura Miesen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, 10
Scientific Reports
Scientific Reports, 10
Scientific Reports
Anti-Thy1.1 transgenic mice develop glomerular lesions that mimic collapsing focal segmental glomerulosclerosis (FSGS) in humans with collapse of the glomerular tuft and marked hyperplasia of the parietal epithelial cells (PECs). Immunostaining of ph
Autor:
Andrew Hall, Prithi S. Bhathal, Alberto Quaglia, Tu Vinh Luong, Corina Cotoi, Jennifer Watkins
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
The histological distinction between acute and chronic liver injury is a challenging aspect of liver histopathology. It is traditionally based on the interpretation of morphological changes to the extracellular matrix (ECM) at sites of hepatocyte los
Autor:
M L T Tha, Jes S. Lindholt, Matthew J. Bown, Maria Bloksgaard, Lars Melholt Rasmussen, Federica Genovese, Lasse Bach Steffensen, S Holm Nielsen, M.A. Karsdal, J H Larsen, Martin Overgaard, D R Hansen, Jane Stubbe, S K Bang-Moeller, Hans Christian Beck, M K T Hong Lin, Gregory T. Jones
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Steffensen, L B, Stubbe, J, Lindholt, J S, Beck, H C, Overgaard, M, Bloksgaard, M, Genovese, F, Holm Nielsen, S, Tha, M L T, Bang-Moeller, S K, Hong Lin, M K T, Larsen, J H, Hansen, D R, Jones, G T, Bown, M J, Karsdal, M A & Rasmussen, L M 2021, ' Basement membrane collagen IV deficiency promotes abdominal aortic aneurysm formation ', Scientific Reports, vol. 11, 12903 . https://doi.org/10.1038/s41598-021-92303-y
Steffensen, L B, Stubbe, J, Lindholt, J S, Beck, H C, Overgaard, M, Bloksgaard, M, Genovese, F, Holm Nielsen, S, Tha, M L T, Bang-Moeller, S K, Hong Lin, M K T, Larsen, J H, Hansen, D R, Jones, G T, Bown, M J, Karsdal, M A & Rasmussen, L M 2021, ' Basement membrane collagen IV deficiency promotes abdominal aortic aneurysm formation ', Scientific Reports, vol. 11, no. 1, 12903 . https://doi.org/10.1038/s41598-021-92303-y
Scientific Reports
Steffensen, L B, Stubbe, J, Lindholt, J S, Beck, H C, Overgaard, M, Bloksgaard, M, Genovese, F, Holm Nielsen, S, Tha, M L T, Bang-Moeller, S K, Hong Lin, M K T, Larsen, J H, Hansen, D R, Jones, G T, Bown, M J, Karsdal, M A & Rasmussen, L M 2021, ' Basement membrane collagen IV deficiency promotes abdominal aortic aneurysm formation ', Scientific Reports, vol. 11, 12903 . https://doi.org/10.1038/s41598-021-92303-y
Steffensen, L B, Stubbe, J, Lindholt, J S, Beck, H C, Overgaard, M, Bloksgaard, M, Genovese, F, Holm Nielsen, S, Tha, M L T, Bang-Moeller, S K, Hong Lin, M K T, Larsen, J H, Hansen, D R, Jones, G T, Bown, M J, Karsdal, M A & Rasmussen, L M 2021, ' Basement membrane collagen IV deficiency promotes abdominal aortic aneurysm formation ', Scientific Reports, vol. 11, no. 1, 12903 . https://doi.org/10.1038/s41598-021-92303-y
Scientific Reports
Abdominal aortic aneurysm (AAA) is a complex disease which is incompletely accounted for. Basement membrane (BM) Collagen IV (COL4A1/A2) is abundant in the artery wall, and several lines of evidence indicate a protective role of baseline COL4A1/A2 in
Autor:
Hiroyuki Koshimizu, Taro Inoue, Kyotaro Ohta, Hiroaki Nakashima, Kinji Ohno, Bisei Ohkawara, Shiro Imagama, Hiroyuki Tomita, Naoki Ishiguro, Shunsuke Kanbara, Akio Masuda, Mikako Ito
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Cervical spondylotic myelopathy (CSM) is caused by chronic compression of the spinal cord and is the most common cause of myelopathy in adults. No drug is currently available to mitigate CSM. Herein, we made a rat model of CSM by epidurally implantin
Autor:
Aida Laurinaviciene, Povilas Treigys, Mindaugas Morkunas, Dovile Zilenaite, Arvydas Laurinavicius
Publikováno v:
Scientific reports, Berlin : Nature research, 2021, vol. 11, no. 1, art. no. 15474, p. [1-13]
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Within the tumor microenvironment, specifically aligned collagen has been shown to stimulate tumor progression by directing the migration of metastatic cells along its structural framework. Tumor-associated collagen signatures (TACS) have been linked
Autor:
Tamar A. J. van den Berg, Marius C. van den Heuvel, Janneke Wiersema-Buist, Jelle Adelmeijer, Gertrude J. Nieuwenhuijs-Moeke, Ton Lisman, Stephan J. L. Bakker, Harry van Goor, TransplantLines Investigators, Robert A. Pol
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports, 11(1):18937. Nature Publishing Group
Scientific Reports, 11(1):18937. Nature Publishing Group
In kidney transplantation, microthrombi and fibrin deposition may lead to local perfusion disorders and subsequently poor initial graft function. Microthrombi are often regarded as donor-derived. However, the incidence, time of development, and poten
Autor:
Birger Dieriks, Maurice A. Curtis, Helen C. Murray, Richard L.M. Faull, Clinton Turner, Taylor J. Stevenson
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Reduced olfactory function (hyposmia) is one of the most common non-motor symptoms experienced by those living with Parkinson’s disease (PD), however, the underlying pathology of the dysfunction is unclear. Recent evidence indicates that α-synucle
Autor:
Martin J. Hoogduijn, Carla C. Baan, L.J.W. van der Laan, Wenda Verschoor, Robert C. Minnee, Jeroen G. H. P. Verhoeven, Dennis A. Hesselink, M. W. F. van den Hoogen, H. Tejeda-Mora, Karin Boer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports, 11(1). Nature Publishing Group
Scientific Reports
Scientific Reports, 11(1). Nature Publishing Group
Scientific Reports
The diagnosis of kidney allograft rejection is based on late histological and clinical markers. Early, specific and minimally-invasive biomarkers may improve rejection diagnosis. Endothelial cells (EC) are one of the earliest targets in kidney transp
Autor:
Peter Valentin Tomazic, A. Perras, Christine Moissl-Eichinger, Axel Wolf, Kaisa Koskinen, Dietmar Thurnher
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
This study aimed to undertake an initial, comparative analysis of the oral salivary microbiome of patients with oral and oropharyngeal squamous cell carcinoma versus healthy controls. This project, conceived as a pilot study, included 11 patients (1
Autor:
Esteban C. Gabazza, Masaaki Toda, Masaaki Ito, Corina N. D’Alessandro-Gabazza, Hiroshi Kawachi, Kunimasa Yan, Yugo Ito, Kensuke Joh, Taro Yasuma, Kan Katayama, Karl Tryggvason, Akiko Tanoue, Kaoru Dohi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports
Crb2 is a cell polarity-related type I transmembrane protein expressed in the apical membrane of podocytes. Knockdown of crb2 causes glomerular permeability defects in zebrafish, and its complete knockout causes embryonic lethality in mice. There are