Zobrazeno 1 - 10
of 27
pro vyhledávání: '"11"'
Autor:
Clément N. David, Monica J. Carson, J. Philip Nance, Tyler A. Landrith, Emma H. Wilson, Kathryn E. McGovern, Shahani Noor, Andre Obenaus, Dimitrios Morikis, Danielle Worth, Reed E.S. Harrison
Publikováno v:
Scientific Reports
Scientific reports, vol 11, iss 1
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Scientific reports, vol 11, iss 1
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Central nervous system (CNS) injury and infection can result in profound tissue remodeling in the brain, the mechanism and purpose of which is poorly understood. Infection with the protozoan parasite Toxoplasma gondii causes chronic infection and inf
Autor:
Kazuhiro Morishita, Tohru Natsume, Tomoya Hirano, Mayumi Soga, Tomohisa Hatta, Takeshi Maruyama, Saki Takayanagi, Kazuki Hattori, Hiroyuki Kagechika, Isao Naguro, Hidenori Ichijo, Motoyuki Ogawa, Kengo Watanabe
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Recent studies have shown that adipose tissue is an immunological organ. While inflammation in energy-storing white adipose tissues has been the focus of intense research, the regulatory mechanisms of inflammation in heat-producing brown adipose tiss
Autor:
Chong Hyun Won, Sun Young Choi, Woo Jin Lee, Mi Ra Yun, Sung Eun Chang, Keon Hee Lee, Hae Kyeong Yoon, Ik Jun Moon
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports
Scientific Reports
Cold atmospheric plasma (CAP) has been incorporated into various fields, including promotion of cutaneous wound healing. Atopic dermatitis (AD) is a chronic cutaneous condition characterized by inflammation-induced skin wounds and impaired skin barri
Autor:
David R. Martinez, Tomohiro Kawano, Ursula Rauch, Joseph S. Palumbo, Leah Rosenfeldt, Vanthana Bharathi, Silvio Antoniak, Clare M. Schmedes, Alice Weithauser, Grant J. Egnatz, Yohei Hisada, Michael Bode, Nigel Mackman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Protease-activated receptor 1 (PAR1) is widely expressed in humans and mice, and is activated by a variety of proteases, including thrombin. Recently, we showed that PAR1 contributes to the innate immune response to viral infection. Mice with a globa
Autor:
Jayden Yamakaze, Zhe Lu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports
Strongly oxidative H2O2 is biologically important, but if uncontrolled, would lead to tissue injuries. Lactoperoxidase (LPO) catalyzes the redox reaction of reducing highly reactive H2O2 to H2O while oxidizing thiocyanate (SCN−) to relatively tissu
Autor:
Arun Chauhan, Brij B. Singh, Pramod Sukumran, Yuyang Sun, Bibhuti B. Mishra, Jitendra Kumar Tripathi, Atul Sharma, Jyotika Sharma
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports
Despite their protective antimicrobial function, neutrophil extracellular traps (NETs) have been implicated in propagation of inflammatory responses in several disease conditions including sepsis. Highly diffusible exogenous ROS produced under such i
Autor:
Yejia Zhang, Maurizio Pacifici, Gabriella Cs-Szabo, Zuozhen Tian, Ling Qin, Motomi Enomoto-Iwamoto, David Gerard, Frances S. Shofer, Lutian Yao
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
We found ADAM8 enzymatic activity elevated in degenerative human intervertebral disc (IVD). Here, we examined the discs in ADAM8-inactivation mice that carry a mutation preventing self-activation of the enzyme. Surprisingly, elevated gene expression
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Scientific Reports
Scientific Reports
Inflammation plays central roles in the immune response. Inflammatory response normally requires higher energy and therefore is associated with glucose metabolism. Our recent study demonstrates that lncRNA HOTAIR plays key roles in NF-kB activation,
Autor:
Enrique Jiménez-Ferrer, José Pedraza-Chaverri, Marisol Méndez-Martínez, Zimri Aziel Alvarado-Ojeda, María Angélica Santana, Maribel Herrera-Ruiz, Gabriela Rosas-Salgado, Beatriz Hernández-Téllez, Gladis Fragoso, Oscar Ramírez-Pliego, Jacquelynne Cervantes-Torres, Celeste Trejo-Moreno, Gerardo Arrellín-Rosas, Alejandro Costet-Mejía, Omar Noel Medina-Campos, Gabriela Castro-Martínez
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Endothelial dysfunction (ED) is a key factor for the development of cardiovascular diseases. Due to its chronic, life-threatening nature, ED only can be studied experimentally in animal models. Therefore, this work was aimed to characterize a murine
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Gut barrier dysfunction is often implicated in pathology following alcohol intoxication and burn injury. MicroRNAs (miRNAs) are negative regulators of gene expression that play a central role in gut homeostasis, although their role after alcohol and