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Autor:
Abdulkadir Tasdelen, Baha Sen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports
miRNAs (or microRNAs) are small, endogenous, and noncoding RNAs construct of about 22 nucleotides. Cumulative evidence from biological experiments shows that miRNAs play a fundamental and important role in various biological processes. Therefore, the
Autor:
Xinlu Wang, Kaili Liao, Guanyu Zhang, Xiaozhong Wang, Jiasheng Xu, Yanhua Wan, Qiwen Ke, Kaihua Zhang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
To screen the key genes in the development of gastric cancer and their influence on prognosis. The GEO database was used to screen gastric cancer-related gene chips as a training set, and the R packages limma tool was used to analyze the differential
Autor:
Nancy J. Cox, Roshan Darji, Emily J. Ross, Hanna Sothers, Emily R Gordon, Balabhaskar Prabhakarpandian, Oakley Baron, Sara J. Cooper, Dustin Haithcock, Richard M. Myers, Kapil Pant
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
The kidney proximal tubule is the primary site for solute reabsorption, secretion and where kidney diseases can originate, including drug-induced toxicity. Two-dimensional cell culture systems of the human proximal tubule cells (hPTCs) are often used
Autor:
Miklós Boldogkői, Dóra Tombácz, Gábor Torma, Ákos Dörmő, Tibor Kalmár, Norbert Moldován, Gábor Gulyás, Zsolt Csabai, Victoria A Jefferson, Zsolt Boldogkői, Zoltán Maróti, Florencia Meyer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Third-generation sequencing is able to read full-length transcripts and thus to efficiently identify RNA molecules and transcript isoforms, including transcript length and splice isoforms. In this study, we report the time-course profiling of the eff
Autor:
Duc-Tinh Pham, Tien-Dzung Tran
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Each cancer type has its own molecular signaling network. Analyzing the dynamics of molecular signaling networks can provide useful information for identifying drug target genes. In the present study, we consider an on-network dynamics model—the ou
Autor:
Pratap D. Bade, Filippo Castiglione, Tamalika Kar, Anurag P. Srivastava, Utkarsh Narsaria, Debashrito Deb, Indraneel Sanyal, Srijita Basak
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-22 (2021)
Scientific reports (Nature Publishing Group) 11 (2021). doi:10.1038/s41598-021-93305-6
info:cnr-pdr/source/autori:Basak S.; Deb D.; Narsaria U.; Kar T.; Castiglione F.; Sanyal I.; Bade P.D.; Srivastava A.P./titolo:In silico designing of vaccine candidate against Clostridium difficile/doi:10.1038%2Fs41598-021-93305-6/rivista:Scientific reports (Nature Publishing Group)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:11
Scientific Reports
Scientific reports (Nature Publishing Group) 11 (2021). doi:10.1038/s41598-021-93305-6
info:cnr-pdr/source/autori:Basak S.; Deb D.; Narsaria U.; Kar T.; Castiglione F.; Sanyal I.; Bade P.D.; Srivastava A.P./titolo:In silico designing of vaccine candidate against Clostridium difficile/doi:10.1038%2Fs41598-021-93305-6/rivista:Scientific reports (Nature Publishing Group)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:11
Scientific Reports
Clostridium difficile is a spore-forming gram-positive bacterium, recognized as the primary cause of antibiotic-associated nosocomial diarrhoea. Clostridium difficile infection (CDI) has emerged as a major health-associated infection with increased i
Autor:
W. G. Li, Matthew D. Ringel, Sandya Liyanarachchi, Pearlly S. Yan, Albert de la Chapelle, Daniel F. Comiskey, Huiling He, Ralf Bundschuh, Altan M. Turkoglu, Pamela Brock
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. The molecular characteristics of histologically normal appearing tissue adjacent to the tumor (NAT) from PTC patients are not well characterized. The aim of this study was t
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
COVID-19 global cases have climbed to more than 33 million, with over a million total deaths, as of September, 2020. Real-time massive SARS-CoV-2 whole genome sequencing is key to tracking chains of transmission and estimating the origin of disease o
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Direct tests of gene function have historically been performed in a limited number of model organisms. The CRISPR/Cas system is species-agnostic, offering the ability to manipulate genes in a range of models, enabling insights into evolution, develop
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports
Recent studies have suggested that platelets have a crucial role in enhancing the survival of circulating tumor cells in the bloodstream and aggravating cancer metastasis. The main function of platelets is to bind to the sites of the damaged vessels