Zobrazeno 1 - 10
of 29
pro vyhledávání: ''
Autor:
Mohamedraed Elshami, Mohammed Ayyad, Mohammed Alser, Ibrahim Al-Slaibi, Balqees M. Mohamad, Maram Albandak, Mohammad F. Dwikat, Shoruq A. Naji, Wejdan S. Isleem, Adela Shurrab, Bashar Yaghi, Yahya Ayyash Qabaja, Fatma K. Hamdan, Raneen R. Sweity, Remah T. Jneed, Khayria A. Assaf, Mohammed M. Hmaid, Iyas I. Awwad, Belal K. Alhabil, Marah N. Alarda, Amani S. Alsattari, Moumen S. Aboyousef, Omar A. Aljbour, Rinad AlSharif, Christy T. Giacaman, Ali Y. Alnaga, Ranin M. Abu Nemer, Nada M. Almadhoun, Sondos M. Skaik, Shurouq I. Albarqi, Bettina Bottcher, Nasser Abu-El-Noor
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Colorectal cancer (CRC) is a frequent cause of cancer-related mortality in the Palestinian population. This cross-sectional study was conducted from July 2019 to March 2020 and examined attitudes toward CRC and colonoscopy, as well as the in
Externí odkaz:
https://doaj.org/article/80f09d036b8b4fcb8f0212674916bd7b
Autor:
Toshiya Miyata, Tamuro Hayama, Tsuyoshi Ozawa, Keijiro Nozawa, Takeyuki Misawa, Takeo Fukagawa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Colorectal cancer (CRC) poses a significant global health challenge, demanding reliable prognostic tools to guide treatment decisions. This study introduces a novel prognostic scoring system, the albumin-total lymphocyte count-RAS index (ALR
Externí odkaz:
https://doaj.org/article/6d00d9245dff4eee8bd5c8b77e34481c
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract This study probes the utility of biomarkers for microsatellite instability (MSI) detection and elucidates the molecular dynamics propelling colorectal cancer (CRC) progression. We synthesized a primer panel targeting 725 MSI loci, informed b
Externí odkaz:
https://doaj.org/article/5383932790b0436ea7e27d0500938385
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The purpose of this study was to investigate the causal association between unhealthy lifestyle style factors and the risk of colorectal cancer, with the aim of preventing the occurrence of colorectal cancer by modifying unhealthy lifestyles
Externí odkaz:
https://doaj.org/article/d2d1cd935f2b449b80858157d253111a
Autor:
Garrett Johnson, Harminder Singh, Ramzi M. Helewa, Kathryn M. Sibley, Kristin A. Reynolds, Charbel El-Kefraoui, Malcolm B. Doupe
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract National consensus recommendations have recently been developed to standardize colorectal tumour localization and documentation during colonoscopy. In this qualitative semi-structured interview study, we identified and contrast the perceived
Externí odkaz:
https://doaj.org/article/84ed103c1d4c4593bc8c725b8d473372
Autor:
Yangbo Li, Pengzhan He, Ying Chen, Jiaming Hu, Beiying Deng, Chuan Liu, Baoping Yu, Weiguo Dong
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Colorectal cancer (CRC) is a prevalent global health issue, with 5-fluorouracil (5-FU) being a commonly used chemotherapeutic agent for its treatment. However, the efficacy of 5-FU is often hindered by drug tolerance. Sodium butyrate (NaB),
Externí odkaz:
https://doaj.org/article/38d3ae8bb8a9437f998fb423f59e3fcc
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-23 (2024)
Abstract The prognosis for patients with colorectal cancer (CRC) remains worse than expected due to metastasis, recurrence, and resistance to chemotherapy. Colorectal cancer stem cells (CRCSCs) play a vital role in tumor metastasis, recurrence, and c
Externí odkaz:
https://doaj.org/article/3d146d6c1a54454abf0546f0ed6f51ed
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Natural killer (NK) cells are closely associated with malignant tumor progression and metastasis. However, studies on their relevance in colorectal cancer (CRC) are limited. We aimed to comprehensively analyze the absolute counts, phenotypes
Externí odkaz:
https://doaj.org/article/6ecaab6f7e0d4ccd8aa28b0f6c0c178e
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract Colorectal cancer (CRC) is a malignant tumor originating from epithelial cells of the colon or rectum, and its invasion and metastasis could be regulated by anoikis. However, the key genes and pathways regulating anoikis in CRC are still unc
Externí odkaz:
https://doaj.org/article/e8264c5d5284422c887d12ed860afae4
Autor:
Weiwei Zheng, Yingchang Guo, Aihemaiti Kahar, Junwei Bai, Qinhui Zhu, Xinli Huang, Yuan Li, Bingyi Xu, Xueshan Jia, Gang Wu, Chao Zhang, Yuanzeng Zhu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Colorectal cancer (CRC) arises via the progressive accumulation of dysregulation in key genes including oncogenes and tumor-suppressor genes. Prostaglandin-endoperoxide synthase 2 (PTGS2, also called COX2) acts as an oncogenic driver in CRC.
Externí odkaz:
https://doaj.org/article/4231b182bb594a42a8ad0c0c2fedbf0e