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pro vyhledávání: ''
Autor:
Martin Friedlander, Robyn H. Guymer, Kamron N. Khan, Roberto Bonelli, Sasha Woods, Jennifer K Trombley, Tjebo F. C. Heeren, Brendan R E Ansell, Catherine A Egan, Melanie Bahlo, Marcus Fruttiger
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Macular Telangiectasia type 2 (MacTel) is an uncommon bilateral retinal disease, in which glial cell and photoreceptor degeneration leads to central vision loss. The causative disease mechanism is largely unknown, and no treatment is currently availa
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Physical exercise has been suggested to reduce the risk of developing Alzheimer’s disease (AD) as well as ameliorate the progression of the disease. However, we recently published results from two large epidemiological studies showing no such benef
Autor:
Tsuyoshi Tsuduki, Kenta Murotani, Taiki Sugimoto, Kenji Toba, Naoki Saji, Takashi Sakurai, Shumpei Niida, Takayoshi Hisada, Ai Kimura
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
Recent studies have revealed an association between the dysregulation of the gut microbiome and dementia. However, whether this dysregulation is associated with mild cognitive impairment (MCI), an early stage of cognitive decline, in patients without
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
The purpose of this systematic review and meta-analysis was to investigate omega-3 fatty acids’ influence on 12 inflammatory biomarkers—LDL, HDL, total cholesterol, TG, HbA1c, Apo AI, Apo AII, Apo B, CRP, TNF-α, glucose, and fasting blood glucos
Autor:
Tatiana Dorfman, Naama Reshef, Uri Gophna, Hilla Knobler, Nirit Keren, Assaf Stein, Leah Reshef, Ishai Lachter, Yoram Kluger, Fred M. Konikoff, Yaakov Maor, Elizabeth E. Half
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Pancreatic cancer (PC) is a leading cause of cancer-related death in developed countries, and since most patients have incurable disease at the time of diagnosis, developing a screening method for early detection is of high priority. Due to its metab
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
This study aims to examine whether perceived poor sleep quality predicts subsequent recurrence of peptic ulcer disease (PUD) in older patients with mild cognitive impairment following Helicobacter pylori eradication and to investigate whether social
Autor:
Olle Melander, Manan Pareek, Bledar Daka, Margret Leosdottir, Peter M. Nilsson, Ulf Lindblad, Michael H. Olsen, John Molvin, Martin Magnusson, Amra Jujic, Lennart Råstam
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019)
Scientific Reports
Molvin, J, Pareek, M, Jujic, A, Melander, O, Råstam, L, Lindblad, U, Daka, B, Leósdóttir, M, Nilsson, P M, Olsen, M H & Magnusson, M 2019, ' Using a Targeted Proteomics Chip to Explore Pathophysiological Pathways for Incident Diabetes : The Malmö Preventive Project ', Scientific Reports, vol. 9, 272 . https://doi.org/10.1038/s41598-018-36512-y
Scientific Reports
Molvin, J, Pareek, M, Jujic, A, Melander, O, Råstam, L, Lindblad, U, Daka, B, Leósdóttir, M, Nilsson, P M, Olsen, M H & Magnusson, M 2019, ' Using a Targeted Proteomics Chip to Explore Pathophysiological Pathways for Incident Diabetes : The Malmö Preventive Project ', Scientific Reports, vol. 9, 272 . https://doi.org/10.1038/s41598-018-36512-y
Multiplex proteomic platforms provide excellent tools for investigating associations between multiple proteins and disease (e.g., diabetes) with possible prognostic, diagnostic, and therapeutic implications. In this study our aim was to explore novel
Autor:
Changhan Chen, Junchen Wang, Yunxia Lv, Xin Zhang, Zhexuan Li, Guancheng Liu, liangjuan Chen, Jinyang Zheng, Leiming Pi, Gengming Cai, Gangcai Zhu, Liming Zhuang, Jiangyi Liu
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports
Head and neck squamous cell carcinoma (HNSCC) is a common malignant cancer that accounts for 5–10% of all cancers. This study aimed to identify essential genes associated with the prognosis of HNSCC and construct a powerful prognostic model for the
Autor:
Syeda Fabeha Husain, Wilson W.S. Tam, Ada Ng, Roger S. McIntyre, Melvyn W. B. Zhang, Roger C.M. Ho, Cyrus S.H. Ho
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
We carried out systematic review and meta-analysis to evaluate whether peripheral levels of pro-inflammatory markers including Interleukin-1 beta (IL-1β), Interleukin-6 (IL-6), Tumor Necrosis Factor-α (TNF- α) and C-Reactive Protein (CRP) are sign
Autor:
Nadeem O. Kaakoush, Cynthia Forest, Danny Mok, Angela Baird, Prue H. Hart, Lavinia Gordon, Terence McGonigle, Roger Bouillon, Borut Klopcic, Shelley Gorman, Simon Ghaly, Ian C. Lawrance, Frances Lloyd
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
Vitamin D has been suggested as a possible adjunctive treatment to ameliorate disease severity in human inflammatory bowel disease. In this study, the effects of diets containing high (D++, 10,000 IU/kg), moderate (D+, 2,280 IU/kg) or no vitamin D (D