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Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.19066. ⟨10.1038/s41598-020-76011-7⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-76011-7⟩
Scientific Reports, Nature Publishing Group, 2020, 10, pp.19066. ⟨10.1101/751289⟩
Scientific Reports, 2020, 10 (1), pp.19066. ⟨10.1038/s41598-020-76011-7⟩
Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.19066. ⟨10.1038/s41598-020-76011-7⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-76011-7⟩
Scientific Reports, Nature Publishing Group, 2020, 10, pp.19066. ⟨10.1101/751289⟩
Scientific Reports, 2020, 10 (1), pp.19066. ⟨10.1038/s41598-020-76011-7⟩
The conditions used to describe the presence of an immune disease are often represented by interaction graphs. These informative, but intricate structures are susceptible to perturbations at different levels. The mode in which that perturbation occur
Autor:
Kanchan Jha, Sriparna Saha
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Protein is the primary building block of living organisms. It interacts with other proteins and is then involved in various biological processes. Protein–protein interactions (PPIs) help in predicting and hence help in understanding the functionali
Autor:
Pharawee Wandee, Yong Poovorawan, Monnat Pongpanich, Monpat Chamnanphon, Apichai Khongphatthanayothin, Koonlawee Nademanee, John Mauleekoonphairoj, Boosamas Sutjaporn, Pajaree Chariyavilaskul
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Scientific Reports
Scientific Reports
Publicly available pharmacogenomics (PGx) databases enable translation of genotype data into clinically actionable information. As variation within pharmacogenes is population-specific, this study investigated the spectrum of 25 clinically relevant p
Autor:
Kyeong Ri Yu, Edward H. Kerns, Xin Xu, Kabir, Jorge Neyra, Pranav Shah, Ðắc-Trung Nguyễn, Vishal B. Siramshetty, Noel Southall, Jordan Williams, Kimloan Nguyen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Hepatic metabolic stability is a key pharmacokinetic parameter in drug discovery. Metabolic stability is usually assessed in microsomal fractions and only the best compounds progress in the drug discovery process. A high-throughput single time point
Autor:
Loredana Moffa, Claudio Moser, S. Piazza, Lorenzo Vittani, Valerio Pompili, Lorenza Dalla Costa, Umberto Salvagnin, Alessandro Cestaro, Mickael Malnoy
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Genome editing via CRISPR/Cas9 is a powerful technology, which has been widely applied to improve traits in cereals, vegetables and even fruit trees. For the delivery of CRISPR/Cas9 components into dicotyledonous plants, Agrobacterium tumefaciens med
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Cells obtained from human saliva are commonly used as an alternative DNA source when blood is difficult or less convenient to collect. Although DNA extracted from saliva is considered to be of comparable quality to that derived from blood, recent stu
Autor:
Shabir H. Wani, Hosam O. Elansary, M. Arumugam Pillai, Nidhi Verma, Viswanathan Chinnusamy, Diaa O. El-Ansary, Bharat Mishra, P. S. Pandey, Jeshima Khan Yasin
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-23 (2020)
Scientific Reports
Scientific Reports
Horsegram (Macrotyloma uniflorum (Lam.) Verdc.) is a drought hardy food and fodder legume of Indo-African continents with diverse germplasm sources demonstrating alternating mechanisms depicting contrasting adaptations to different climatic zones. Ti
Autor:
Marcus B. Smolka, William J. Comstock, Shannon Marshall, Vitor M. Faça, Shagun Gupta, Jennifer H. Tieu, Ethan J. Sanford, Haiyuan Yu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
The maintenance of genomic stability relies on DNA damage sensor kinases that detect DNA lesions and phosphorylate an extensive network of substrates. The Mec1/ATR kinase is one of the primary sensor kinases responsible for orchestrating DNA damage r
Autor:
C. Suarez Pantaleon, Delphine Larose, N. Desroche, Anne-Catherine Huet, Philippe Delahaut, Riccardo Marega, P. Arbault, Nathalie Gillard, M. Paulus
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
The control of antibody specificity plays pivotal roles in key technological fields such as diagnostics and therapeutics. During the development of immunoassays (IAs) for the biosensing of pathogens in food matrices, we have found a way to rationaliz
Autor:
Viorel Iulian Suica, Gabriel Socol, Emanuel Dragan, Sorin Mihai Croitoru, Livia Elena Sima, Raluca Maria Boteanu, Marioara Chiritoiu, Constantin Vlagioiu, Luminita Ivan, Elena Uyy, Valentina Grumezescu, Florentina Safciuc, Felicia Antohe
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Due to their excellent mechanical and biocompatibility properties, titanium-based implants are successfully used as biomedical devices. However, when new bone formation fails for different reasons, impaired fracture healing becomes a clinical problem