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Autor:
Iren R. Umarova, L. A. Uroshlev, R. V. Polozov, Fyodor A. Kondrashov, Il'icheva Ia, Yury D. Nechipurenko, L. A. Panchenko, Eldar T. Abdullaev, S. L. Grokhovsky
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-5 (2020)
Scientific Reports
Scientific Reports
In the course of sample preparation for Next Generation Sequencing (NGS), DNA is fragmented by various methods. Fragmentation shows a persistent bias with regard to the cleavage rates of various dinucleotides. With the exception of CpG dinucleotides
Autor:
Richard H. Wagner, Gurjit S. Sidhu, Layla Schuster, Eric Li, Lin Liu, Taimour Y. Langaee, Gary P. Wang, Ryan Tamashiro
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
HIV drug resistance is a major threat to achieving long-term viral suppression in HIV-positive individuals. Drug resistant HIV variants, including minority variants, can compromise response to antiretroviral therapy. Many studies have investigated th
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific reports
Scientific Reports
Scientific reports
A panel of 32 candidate reference genes was used to identify the most stable genes for gene normalisation in quantitative RT-PCR studies using endometrial biopsies obtained from women with endometrial cancer (type 1 or type 2) and without cancer (con
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-6 (2020)
Scientific Reports
Scientific Reports
Bioinformatic analysis reveals an enrichment of putative DNA:RNA hybrid G-quadruplex-forming sequences (PHQS) on both sides of the transcription start sites (TSSs) in the genome of warm-blooded animals, suggesting a positive selection of PHQSs in evo
Autor:
Daisuke Takahashi, Gen Matsumae, Norimasa Iwasaki, Tomohiro Onodera, Hend Alhasan, Yuan Tian, Masanari Hamasaki, Taku Ebata, Mohamad Alaa Terkawi
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Accumulating evidence suggests that synovitis is associated with osteoarthritic process. Macrophages play principal role in development of synovitis. Our earlier study suggests that interaction between cartilage fragments and macrophages exacerbates
Autor:
Maria Colomba Comes, C. Di Natale, Lina Ghibelli, Davide Di Giuseppe, Eugenio Martinelli, Arianna Mencattini, Paola Casti, Francesca Romana Bertani, Francesca Corsi, Luca Businaro, Maria Carla Parrini
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific reports (Nature Publishing Group) 10 (2020). doi:10.1038/s41598-020-64246-3
info:cnr-pdr/source/autori:Mencattini, A.; Di Giuseppe, D.; Comes, M. C.; Casti, P.; Corsi, F.; Bertani, F. R.; Ghibelli, L.; Businaro, L.; Di Natale, C.; Parrini, M. C.; Martinelli, E./titolo:Discovering the hidden messages within cell trajectories using a deep learning approach for in vitro evaluation of cancer drug treatments/doi:10.1038%2Fs41598-020-64246-3/rivista:Scientific reports (Nature Publishing Group)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
Scientific Reports
Scientific reports (Nature Publishing Group) 10 (2020). doi:10.1038/s41598-020-64246-3
info:cnr-pdr/source/autori:Mencattini, A.; Di Giuseppe, D.; Comes, M. C.; Casti, P.; Corsi, F.; Bertani, F. R.; Ghibelli, L.; Businaro, L.; Di Natale, C.; Parrini, M. C.; Martinelli, E./titolo:Discovering the hidden messages within cell trajectories using a deep learning approach for in vitro evaluation of cancer drug treatments/doi:10.1038%2Fs41598-020-64246-3/rivista:Scientific reports (Nature Publishing Group)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
Scientific Reports
We describe a novel method to achieve a universal, massive, and fully automated analysis of cell motility behaviours, starting from time-lapse microscopy images. The approach was inspired by the recent successes in application of machine learning for
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
DNA barcoding is a valuable tool to support species identification with broad applications from traditional taxonomy, ecology, forensics, food analysis, and environmental science. We introduce Microfluidic Enrichment Barcoding (MEBarcoding) for plant
Autor:
Edit Tímár, György Pósfai, Zsuzsanna Gyorfy, István Nagy, Viktor Vernyik, Ádám Györkei, Ildikó Karcagi, Balázs Papp
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Artificial simplification of bacterial genomes is thought to have the potential to yield cells with reduced complexity, enhanced genetic stability, and improved cellular economy. Of these goals, economical gains, supposedly due to the elimination of
Autor:
Caroline S. Moffat, Darcy A. B. Jones, Shiv Meka, Suman Rakshit, Paula Moolhuijzen, Catherine Rawlinson
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Metabolite identification is the greatest challenge when analysing metabolomics data, as only a small proportion of metabolite reference standards exist. Clustering MS/MS spectra is a common method to identify similar compounds, however interrogation
Autor:
James T. Rosenbaum, Suzanne S. Fei, Stephen R. Planck, Robert P. Searles, Brett Davis, Kimberly Ogle, Christina A. Harrington, Lucia Carbone, Dongseok Choi, Jessica Minnier
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
J Biomol Tech
Scientific Reports
J Biomol Tech
Peripheral blood is a highly accessible biofluid providing a rich source of information about human physiology and health status. However, for studies of the blood transcriptome with RNA sequencing (RNA-Seq) techniques, high levels of hemoglobin mRNA