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Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.19066. ⟨10.1038/s41598-020-76011-7⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-76011-7⟩
Scientific Reports, Nature Publishing Group, 2020, 10, pp.19066. ⟨10.1101/751289⟩
Scientific Reports, 2020, 10 (1), pp.19066. ⟨10.1038/s41598-020-76011-7⟩
Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.19066. ⟨10.1038/s41598-020-76011-7⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-76011-7⟩
Scientific Reports, Nature Publishing Group, 2020, 10, pp.19066. ⟨10.1101/751289⟩
Scientific Reports, 2020, 10 (1), pp.19066. ⟨10.1038/s41598-020-76011-7⟩
The conditions used to describe the presence of an immune disease are often represented by interaction graphs. These informative, but intricate structures are susceptible to perturbations at different levels. The mode in which that perturbation occur
Autor:
C. Suarez Pantaleon, Delphine Larose, N. Desroche, Anne-Catherine Huet, Philippe Delahaut, Riccardo Marega, P. Arbault, Nathalie Gillard, M. Paulus
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
The control of antibody specificity plays pivotal roles in key technological fields such as diagnostics and therapeutics. During the development of immunoassays (IAs) for the biosensing of pathogens in food matrices, we have found a way to rationaliz
Autor:
Mine-Hsine Wu, Chuan Shih, Hsiao-Fu Chang, Chun-Ping Chang, Lun K. Tsou, Shau-Hua Ueng, Shiu Hwa Yeh, Chiung-Tong Chen, Yi-Yu Ke, Jen-Shin Song, Sheng-Ren Chen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Machine learning is a well-known approach for virtual screening. Recently, deep learning, a machine learning algorithm in artificial neural networks, has been applied to the advancement of precision medicine and drug discovery. In this study, we perf
Autor:
Thiruni N. Adikari, Vanessa W X Lim, Praveen Weeratunga, Senaka Rajapakse, Deepika Fernando, Katja Fink, Braulio M. Valencia, Nasir Riaz, Andrew R. Lloyd, Martin A. Smith, Preston Leung, Rowena A. Bull, Tun-Linn Thein, Chathurani Sigera, Fabio Luciani, Chaturaka Rodrigo, Yee Sin Leo, Hui Li, Kirston Barton
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Current methods for dengue virus (DENV) genome amplification, amplify parts of the genome in at least 5 overlapping segments and then combine the output to characterize a full genome. This process is laborious, costly and requires at least 10 primers
Autor:
Nebojsa Janjic, Zuben E. Sauna, Katarzyna I. Jankowska, William C. Chang, Amy D. Gelinas, Wojciech Jankowski, H.A. Daniel Lagassé, Joseph R. McGill
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Reliable and reproducible monitoring of the conformational state of therapeutic protein products remains an unmet technological need. This need is amplified by the increasing number of biosimilars entering the drug development pipeline as many brande
Autor:
Yao Lin, Weimin Zhong, Bin Chen, Hongbin Zhong, Chaoqun Huang, Jiyi Huang, Maoshu Zhu, Miaoxuan Chen, Jianqiong Lin, Ying Lin
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Clear cell renal cell carcinoma (ccRCC) is the most common type of renal cell carcinoma (RCC). Despite the existing extensive research, the molecular and pathogenic mechanisms of ccRCC are elusive. We aimed to identify the immune-related lncRNA signa
Autor:
Zijie Yuan, Youde Cao, Yonghua Yuan, Zhonghua Deng, Yanghua Yue, Jie Chen, Lu Wang, Menghua Zhao, Chaochao Tan
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Kawasaki disease (KD) is a multi-systemic vasculitis of unknown etiology that occurs mainly in children, and the disturbance of gut microbiota is generally believed to cause a hyperimmune reaction triggering KD. The aim of the study was to investigat
Autor:
Jose Jaimes, Mapaseka L. Seheri, Michael D. Bowen, Sebotsana Rasebotsa, Martin M. Nyaga, Saheed Sabiu, Didier Murenzi, Jason M. Mwenda, Kebareng Giliking Rakau, Milton T. Mogotsi, Peter N. Mwangi, M. Jeffrey Mphahlele, Narcisse Muganga, Leon Mutesa, N.B. Magagula, Jeannine Uwimana, Lisine Tuyisenge, Mathew D. Esona
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-22 (2020)
Scientific Reports
Scientific Reports
Rwanda was the first low-income African country to introduce RotaTeq vaccine into its Expanded Programme on Immunization in May 2012. To gain insights into the overall genetic make-up and evolution of Rwandan G1P[8] strains pre- and post-vaccine intr
Autor:
Matthew Inkman, Fiona Ruiz, Kay Jayachandran, Thomas M. Ellis, Yufeng Wu, Christopher A. Miller, Jin Zhang, Akinyemi I. Ojesina, Michael D. McLellan, Julie K. Schwarz
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Accurate HPV genotyping is crucial in facilitating epidemiology studies, vaccine trials, and HPV-related cancer research. Contemporary HPV genotyping assays only detect
Autor:
Heba Z. Sailem, Ayman Al Haj Zen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Angiogenesis plays a key role in several diseases including cancer, ischemic vascular disease, and Alzheimer’s disease. Chemical genetic screening of endothelial tube formation provides a robust approach for identifying signalling components that i