Zobrazeno 1 - 10
of 708
pro vyhledávání: ''
Autor:
Joo-ri Kim-Kaneyama, Shogo Haraguchi, Xiao-Feng Lei, Tomokatsu Omoto, Lin Gao, Akira Miyazaki, Masahito Noguchi, Aya Miyauchi, Takuro Miyazaki
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Accumulated evidence suggests that activated pancreatic stellate cells (PSCs) serve as the main source of the extracellular matrix proteins accumulated under the pathological conditions leading to pancreatic fibrosis in chronic pancreatitis (CP). How
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Platelet Derived Growth Factor Receptor (PDGFR) signaling is a central mitogenic pathway in development, as well as tissue repair and homeostasis. The rules governing the binding of PDGF ligand to the receptor to produce activation and downstream sig
Autor:
Patrick M Noone, Masayuki Yamamoto, Haranatha R. Potteti, Thomas W. Kensler, Narsa M. Reddy, Chandra Mohan Tamatam, Aparna Ankireddy, Sekhar P. Reddy
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Bronchopulmonary dysplasia (BPD) is a chronic disease of preterm babies with poor clinical outcomes. Nrf2 transcription factor is crucial for cytoprotective response, whereas Keap1—an endogenous inhibitor of Nrf2 signaling—dampens these protectiv
Autor:
Moo Kyun Park, Su Ji Kim, Young Rok Seo, An Soo Jang, Nahyun Kim, Jae Jun Song, Bu Soon Son, Hyun Soo Kim, So Hyeon Park
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Airborne pollutants have detrimental effect on the human body and the environment. Diesel exhaust particles (DEPs) are known to be major component of particulate matter (PM) and cause respiratory diseases and neurotoxicity. However, the effects of ai
Autor:
Tan Xiuwen, Chen Zhang, Jin Qing, Liu Guifen, Zhang Xianglun, You Wei, Lin Haichao, Zhao Hongbo, Liu Xiaomu, Wei Chen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
Previously, we found that mevalonic acid stimulates 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGR) expression in bovine intramuscular adipocytes to influence adipocyte differentiation. However, any direct links among HMGR, steroidogenic gene
Autor:
Olatunde P. Olademehin, Fu Chen, Cheolho Sim, Chengyin Liu, Binayak Rimal, Sung Joon Kim, Nathaniel F. Adegboyega
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Culex pipiens is a major carrier of the West Nile Virus, the leading cause of mosquito-borne disease in the continental United States. Cx. pipiens survive overwinter through diapause which is an important survival strategy that is under the control o
Autor:
Isao Hara, Tadasuke Komori, Yoshihiro Morikawa, Atsushi Miyajima, Shimpei Yamashita, Yasuo Kohjimoto
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Oncostatin M (OSM), a member of the IL-6 family of cytokines, has important roles in renal diseases. The relationship between OSM and kidney stone disease, however, remains unclear. To investigate the roles of OSM in the development of kidney stone d
Autor:
Wei Wei, Yinghua Hao, Li Yuxia, Liu Yajing, Fubo Zhong, Jia-Jing Dai, Zhengyu Fang, Yadan Zheng
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Several literature has shown that salinomycin (Sal) is able to kill various types of cancer cells through different signaling pathways. However, its effect on melanoma has seldom been reported. We examined the anti-cancer efficacy of Sal in melanoma
Autor:
Gwo Jyh Chang, Ho Yen Chueh, Ming-Jer Hsieh, Hsiu Yun Huang, Yuling Lin, Jong-Hwei S. Pang, Cheng-Hung Lee
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
BPC 157-activated endothelial nitric oxide synthase (eNOS) is associated with tissue repair and angiogenesis as reported in previous studies. However, how BPC 157 regulates the vasomotor tone and intracellular Src-Caveolin-1 (Cav-1)-eNOS signaling is
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Nerve injury-induced protein 1 (Ninjurin 1, Ninj1) is a cell adhesion molecule responsible for cell-to-cell interactions between immune cells and endothelial cells. In our previous paper, we have shown that Ninj1 plays an important role in the infilt