Zobrazeno 1 - 10
of 95
pro vyhledávání: ''
Autor:
Qinfeng Mu, Jun Zhang, Ying Zhou, Haixiang Xue, Tongbing Chen, Jisheng Liu, Miaomei Yu, Guanghua Luo
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
Prior studies have shown that apolipoprotein M (APOM) is involved in the development of some cancers. Here we investigated the effects of APOM on larynx cancer (LC). 20 patients with vocal cord polyps and 18 patients with LC were included in this stu
Autor:
Peter Bergman, Laia Gorchs, Alisa Knauf, Elena Rangelova, Rainer Heuchel, Chanté Mayer, Sultan Ahmed, Mattias Svensson, Carlos Fernández Moro, Helen Kaipe
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
The pancreatic tumour stroma is composed of phenotypically heterogenous cancer-associated fibroblasts (CAFs) with both pro- and anti-tumorigenic functions. Here, we studied the impact of calcipotriol, a vitamin D3 analogue, on the activation of human
Autor:
Wei Wei, Yinghua Hao, Li Yuxia, Liu Yajing, Fubo Zhong, Jia-Jing Dai, Zhengyu Fang, Yadan Zheng
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Several literature has shown that salinomycin (Sal) is able to kill various types of cancer cells through different signaling pathways. However, its effect on melanoma has seldom been reported. We examined the anti-cancer efficacy of Sal in melanoma
Autor:
Gavin W. Wilson, Sangeetha N Kalimuthu, Jonathan Allen, Nikolina Radulovich, Mathieu Derouet, Ming-Sound Tsao, Gail Darling, Jonathan C. Yeung, Christine Ng
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Esophageal adenocarcinoma has few known recurrent mutations and therefore robust, reliable and reproducible patient-specific models are needed for personalized treatment. Patient-derived organoid culture is a strategy that may allow for the personali
Autor:
Kenneth Aldape, Sheila Mansouri, Yasin Mamatjan, Suganth Suppiah, Gelareh Zadeh, Shirin Karimi, Farshad Nassiri, Olivia Singh, Jeff C. Liu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Management of clinically aggressive meningiomas is a considerable challenge. PD-L1 induced immune suppression has increasingly gained attention in clinical management of cancer; however, to date, the clinical significance and regulatory mechanisms of
Distinct tumor immune microenvironments in primary and metastatic lesions in gastric cancer patients
Autor:
Chang Gok Woo, Hyo Yung Yun, Hee Kyung Kim, Su-Hyung Park, Seung Myoung Son, Hyung-Don Kim, Jihyun Kwon, June Young Koh, Hongsik Kim, Tae Yong Kim, Minsuk Kwon, Hye Sook Han, Yaewon Yang, Dae Hoon Kim, Eui-Cheol Shin
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
This study compared the tumor immune microenvironments (TIMEs) of primary gastric cancer (PGC) and paired metastatic gastric cancer (MGC). CD4+ and CD8+ T-cell density and PD-L1 expression were evaluated by multiplex immunohistochemistry, DNA mismatc
Autor:
Shuji Momose, Michihide Tokuhira, Morihiro Higashi, Yuka Tanaka, Takahisa Yamashita, Akiko Adachi, Jun-ichi Tamaru, Toshiki Watanabe, Masahiro Kizaki
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
MYC-associated factor X (MAX) is a protein in the basic helix-loop-helix leucine zipper family, which is ubiquitously and constitutively expressed in various normal tissues and tumors. MAX protein mediates various cellular functions such as prolifera
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Non-small cell lung cancer (NSCLC) is a common type of lung cancer, characterized by a poor prognosis. In the last several years, more and more studies have demonstrated the significant roles played by circular RNAs (circRNAs) in different human tumo
Autor:
Johannes H. Dreyer, Maike Büttner-Herold, Laura Werner, Ulrike Grittner, Gerald Niedobitek, David Hartmann, Mário Henrique M. Barros
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Commonly attributed to the prevalence of M2 macrophages, tumor-associated macrophages (TAM) are linked to poor outcome in Hodgkin lymphoma (HL). MYC is supposed to control the expression of M2-specific genes in macrophages, and deficiency in MYC-posi
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific reports
Scientific Reports
Scientific reports
A panel of 32 candidate reference genes was used to identify the most stable genes for gene normalisation in quantitative RT-PCR studies using endometrial biopsies obtained from women with endometrial cancer (type 1 or type 2) and without cancer (con