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Publikováno v:
Scientia Pharmaceutica
Volume 89
Issue 3
Scientia Pharmaceutica, Vol 89, Iss 30, p 30 (2021)
Volume 89
Issue 3
Scientia Pharmaceutica, Vol 89, Iss 30, p 30 (2021)
Human serum albumin (HSA) is the most abundant human plasma protein. HSA plays a crucial role in many binding endos- and exogenous substances, which affects their pharmacological effect. The innovative aspect of the study is not only the interaction
Publikováno v:
Scientia Pharmaceutica, Vol 88, Iss 34, p 34 (2020)
Scientia Pharmaceutica
Volume 88
Issue 3
Scientia Pharmaceutica
Volume 88
Issue 3
Our previous study showed that water-soluble fiber from bengkoang (Pachyrizus erosus (L.) Urban) fiber extract (BFE) and bengkoang fiber fraction B (BFE-B) have phagocytic activity and modulation of cytokine production in vitro. The present study eva
Publikováno v:
Scientia Pharmaceutica
Volume 78
Issue 2
Pages 233-248
Volume 78
Issue 2
Pages 233-248
Antidepressants are psychiatric agents used for the treatment of different types of depression being at present amongst the most commonly prescribed drug, while their effectiveness and adverse effects are the subject of many studies and competing cla
Publikováno v:
Scientia Pharmaceutica
Volume 74
Issue 1
Pages 59-75
Volume 74
Issue 1
Pages 59-75
Artemether (ART) is an efficacious anti-malarial drug that also displays antischistosomal properties. Laboratory studies have found that ART curtails the development of schistosoma worms and thus prevents morbidity. Grapefruit juice was found to inte
Publikováno v:
Scientia Pharmaceutica
Scientia Pharmaceutica; Volume 85; Issue 2; Pages: 16
Scientia Pharmaceutica; Volume 85; Issue 2; Pages: 16
Vernonia amygdalina has been shown to have antioxidant activity, and is also expected to have hepatoprotective activity. This study was conducted to study the effect of V. amygdalina ethanol extracts on intoxicated rat livers. Fresh leaves were extra
Publikováno v:
Scientia Pharmaceutica. 78:720-720
At least three enzymes (i. e., trypsin, chymotrypsin and neutrophil elastase) are responsible for the degradation of salmon calcitonin (sCT) in the human body [1]. Here, we investigated how these proteinases affect drug disposition of sCT in the lung
Publikováno v:
Scientia Pharmaceutica. 78:718-718
Topotecan (TPT) is a semi-synthetic derivative of the natural extract camptothecin, which has been found to act as an inhibitor of the DNA enzyme topoisomerase I in a specific and reversible fashion. The drug undergoes reversible hydrolysis from the
Publikováno v:
Scientia Pharmaceutica. 77:241-241
The norepinephrine (= noradrenaline) transporter (NET) belongs besides serotonin and dopamine transporters to the family of monoamine transporters and mediates the re-uptake of norepinephrine released from neurons. Therefore, it is an important regul