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Discoidin domain receptor 2 regulates aberrant mesenchymal lineage cell fate and matrix organization
Autor:
Chase A. Pagani, Alec C. Bancroft, Robert J. Tower, Nicholas Livingston, Yuxiao Sun, Jonathan Y. Hong, Robert N. Kent, Amy L. Strong, Johanna H. Nunez, Jessica Marie R. Medrano, Nicole Patel, Benjamin A. Nanes, Kevin M. Dean, Zhao Li, Chunxi Ge, Brendon M. Baker, Aaron W. James, Stephen J. Weiss, Renny T. Franceschi, Benjamin Levi
Publikováno v:
Science advances. 8(51)
Extracellular matrix (ECM) interactions regulate both the cell transcriptome and proteome, thereby determining cell fate. Traumatic heterotopic ossification (HO) is a disorder characterized by aberrant mesenchymal lineage (MLin) cell differentiation,