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Publikováno v:
Schizophrenia Bulletin. 48:447-456
Sleep and circadian rhythm dysfunction is prevalent in schizophrenia, is associated with distress and poorer clinical status, yet remains an under-recognized therapeutic target. The development of new therapies requires the identification of the prim
Autor:
Karin J. H. Verweij, Rafik Tadros, Jentien M Vermeulen, Robyn E Wootton, Damiaan Denys, Eleanor Sanderson, Abdel Abdellaoui, Connie R. Bezzina, Marcus R. Munafò, Jorien L. Treur, Rada R Veeneman
Publikováno v:
Schizophrenia bulletin, 48(2), 463-473. Oxford University Press
Veeneman, R R, Vermeulen, J M, Abdellaoui, A, Sanderson, E C M, Wootton, R E, Tadros, R, Bezzina, C R, Denys, D, Munafo, M R, Verweij, K J H & Treur, J L 2021, ' Exploring the Relationship Between Schizophrenia and Cardiovascular Disease : A Genetic Correlation and Multivariable Mendelian Randomization Study ', Schizophrenia Bulletin . https://doi.org/10.1093/schbul/sbab132
Veeneman, R R, Vermeulen, J M, Abdellaoui, A, Sanderson, E C M, Wootton, R E, Tadros, R, Bezzina, C R, Denys, D, Munafo, M R, Verweij, K J H & Treur, J L 2021, ' Exploring the Relationship Between Schizophrenia and Cardiovascular Disease : A Genetic Correlation and Multivariable Mendelian Randomization Study ', Schizophrenia Bulletin . https://doi.org/10.1093/schbul/sbab132
ImportanceIndividuals with schizophrenia have a reduced life-expectancy compared to the general population, largely due to an increased risk of cardiovascular disease (CVD). Clinical and epidemiological studies have been unable to fully unravel the n
Autor:
Emma M. Parrish, Dimitri Perivoliotis, Michael L. Thomas, Hannah C. Lykins, Amber V Keller, Elizabeth W. Twamley, Eric Granholm, Zanjbeel Mahmood, Jason Holden
Publikováno v:
Schizophr Bull
Objective Negative symptoms and cognitive impairment in schizophrenia (SZ) remain unmet treatment needs as they are highly prevalent, associated with poor functional outcomes, and resistant to pharmacologic treatment. The current pilot randomized con
Autor:
Victor J. Pokorny, Scott R. Sponheim
Publikováno v:
Schizophr Bull
Background Atypical auditory processing (AAP) in psychotic psychopathology is evident in early (N1), mid-latency (P2/N2/mismatch negativity), and late (P3) neural responses. The influence of attention on AAP, and how temporal stages of AAP are associ
Autor:
David Edmund Johannes Linden, Michael Conlon O'Donovan, Thomas M. Lancaster, Stavros I. Dimitriadis, Stan Zammit, Gavin Perry
Publikováno v:
Schizophrenia Bulletin, 48(2), 524-532. Oxford University Press
Lancaster, T M, Dimitriadis, S I, Perry, G, Zammit, S, O'Donovan, M C & Linden, D E J 2021, ' Morphometric analysis of structural MRI using schizophrenia meta-analytic priors distinguish patients from controls in two independent samples and in a sample of individuals with high polygenic risk ', Schizophrenia Bulletin . https://doi.org/10.1093/schbul/sbab125
Lancaster, T M, Dimitriadis, S I, Perry, G, Zammit, S, O'Donovan, M C & Linden, D E J 2021, ' Morphometric analysis of structural MRI using schizophrenia meta-analytic priors distinguish patients from controls in two independent samples and in a sample of individuals with high polygenic risk ', Schizophrenia Bulletin . https://doi.org/10.1093/schbul/sbab125
Schizophrenia (SCZ) is associated with structural brain changes, with considerable variation in the extent to which these cortical regions are influenced. We present a novel metric that summarises individual structural variation across the brain, whi
Publikováno v:
Schizophr Bull
Based on findings from cognitive science, it has been theorized that the reductions in motivation and goal-directed behavior in people with psychosis could stem from impaired episodic memory. In the current meta-analysis, we investigated this putativ
Publikováno v:
Schizophrenia Bulletin. 48:325-334
A cross-sectional association between visual impairment and psychosis exists, but longitudinal evidence from children and young people is limited. We investigated whether childhood visual acuity was associated with subsequent psychotic experiences. O
Autor:
Andrey A. Shabalin, Emily DiBlasi, Erik Christensen, Eric T. Monson, Douglas Gray, Amanda V. Bakian, Danli Chen, Hilary Coon, Brooks R. Keeshin, Anna R. Docherty, Qingqin Li
Publikováno v:
Schizophr Bull
Approximately 5% of individuals with schizophrenia die from suicide. However, suicide in psychosis is still poorly characterized, partly due to a lack of adequate population-based clinical or genetic data on suicide death. The Utah Suicide Genetics R
Autor:
Vanessa Ermiliou, Nikolaos Nianiakas, Ioannis Kosteletos, Marina Voulgaraki, Lida-Alkisti Xenaki, Evaggelia Psarra, Ilias I Vlachos, Karen Tangmose, Stefania Foteli, Stefanos Dimitrakopoulos, Micah Cearns, Toni Meritt, Anne Sigvard, Mette Olaf Nielsen, Christos Pantelis, Rigas F Soldatos, Bjørn H Ebdrup, Warda Syeda, Irene Ralli, Alex Hatzimanolis, Theoni F Triantafyllou, Nikos C. Stefanis, Costas T. Kollias, Birte Glenthøj, Kirsten Borup Bojesen, Leonidas Mantonakis, Karen Sando Ambrosen, Aggeliki Ntigridaki, Mikkel E. Sørensen, Mirjana Selakovic, Nikolaos Koutsouleris, Pentagiotissa Stefanatou
Publikováno v:
Schizophr Bull
Background Validated clinical prediction models of short-term remission in psychosis are lacking. Our aim was to develop a clinical prediction model aimed at predicting 4−6-week remission following a first episode of psychosis. Method Baseline clin
Autor:
Yuan Xiao, Rebekka Lencer, Hengyi Cao, Na Hu, Su Lui, Xia Wei, Jiaxin Zeng, Qiyong Gong, John A. Sweeney, Wenjing Zhang
Publikováno v:
Schizophr Bull
It has previously been shown that cerebello-thalamo-cortical (CTC) hyperconnectivity is likely a state-independent neural signature for psychosis. However, the potential clinical utility of this change has not yet been evaluated. Here, using fMRI and