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Autor:
Haifeng Yan, Guorui Zhao, Kangguang Lin, Way K.W. Lau, Chanyu Wang, Ruiwang Huang, Chichen Zhang, Ruibin Zhang, Shijun Qiu
Publikováno v:
Schizophrenia Bulletin
Schizophrenia (SZ) and bipolar disorder (BD) share some similarities in terms of genetic-risk genes and abnormalities of gray-matter structure in the brain, but white matter (WM) abnormalities have not been studied in depth. We undertook a comparativ
Autor:
Petra V. Viher, Werner Strik, Andrea Federspiel, Sebastian Walther, Katharina Stegmayer, Roland Wiest, Tobias Bracht, Stephan Bohlhalter
Publikováno v:
Viher, Petra Verena; Stegmayer, Katharina Deborah Lena; Bracht, Tobias; Federspiel, Andrea; Bohlhalter, Stephan; Strik, Werner; Wiest, Roland; Walther, Sebastian (2022). Neurological Soft Signs Are Associated With Altered White Matter in Patients With Schizophrenia. Schizophrenia bulletin, 48(1), pp. 220-230. Oxford University Press 10.1093/schbul/sbab089
Schizophrenia Bulletin
Schizophrenia Bulletin
Neurological soft signs (NSS) are related to grey matter and functional brain abnormalities in schizophrenia. Studies in healthy subjects suggest, that NSS are also linked to white matter. However, the association between NSS and white matter abnorma
Autor:
Xiao Chen Tang, Tao Chen, Lin Lin Zhou, Ye Gang Hu, Chun Bo Li, Yan Yan Wei, Ji Jun Wang, Ying Ying Tang, LiHua Xu, Tianhong Zhang, Hui Ru Cui
Publikováno v:
Schizophr Bull
Objectives Patients with psychiatric disorders have an increased risk of cardiovascular pathologies. A bidirectional feedback model between the brain and heart exists widely in both psychotic and nonpsychotic disorders. The aim of this study was to c
Autor:
Umberto Balottin, Eleonora Filosi, Renato Borgatti, Paolo Fusar-Poli, Silvia Molteni, Elena Ballante, Martina Maria Mensi, Melanie Iorio
Publikováno v:
Schizophr Bull
There is limited research in adolescents at risk for psychosis. The new Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition attenuated psychosis syndrome (DSM-5 APS) criteria have not been validated in this group. We conducted a RECO
Autor:
Carol A. Tamminga, Dean Sabatinelli, Godfrey D. Pearlson, David Parker, John A. Sweeney, Rebekah Trotti, Sunny Abdelmageed, Sarah K. Keedy, Elliot S. Gershon, Brett A. Clementz, Matcheri S. Keshavan, Jennifer E. McDowell
Publikováno v:
Schizophr Bull
Impaired emotional processing and cognitive functioning are common in schizophrenia, schizoaffective disorder, and bipolar disorders, causing significant socioemotional disability. While a large body of research demonstrates abnormal cognition/emotio
Autor:
Shuo Chen, Stephanie M. Hare, Shuping Tan, Yanfang Zhou, Fengmei Fan, Ping Zhang, Junchao Huang, Mark D. Kvarta, Heather Bruce, Peter Kochunov, Zhiren Wang, Jinghui Tong, Li Tian, L. Elliot Hong, Wei Feng, Yunlong Tan, Eric L. Goldwaser, Fude Yang, Yimin Cui, Baopeng Tian, Song Chen
Publikováno v:
Schizophr Bull
Insufficient or lack of response to antipsychotic medications in some patients with schizophrenia is a major challenge in psychiatry, but the underlying mechanisms remain unclear. Two seemingly unrelated observations, cerebral white matter and N-meth
Autor:
Laurent Boyer, Pierre-Michel Llorca, Anderson Loundou, Christophe Lançon, Damien Etchecopar-Etchart, T Korchia, Guillaume Fond, Pascal Auquier
Publikováno v:
Schizophr Bull
Comorbid major depressive disorder (MDD) in schizophrenia (SZ; SZ-MDD) has been identified as a major prognostic factor. However, the prevalence and associated factors of SZ-MDD have never been explored in a meta-analysis. All studies assessing the p
Neural Compensation Mechanisms of Siblings of Schizophrenia Patients as Revealed by High-Density EEG
Autor:
Janir Nuno da Cruz, Maya Roinishvili, Ophélie Favrod, Andreas Brand, Michael H. Herzog, Albulena Shaqiri, Patrícia Figueiredo, Eka Chkonia
Publikováno v:
Schizophr Bull
Visual backward masking (VBM) deficits are candidate endophenotypes of schizophrenia indexing genetic liability of the disorder. In VBM, a target is followed by a mask that deteriorates target perception. Schizophrenia patients and, to a lesser exten
Autor:
Feng Zhu, Bin Yan, Binbin Zhao, Qingyan Ma, Xiancang Ma, Wei Wang, Jie Zheng, Lihong Yang, Jian Yang, Xiaoyan He, Yajuan Fan, Ling Bai
Publikováno v:
Schizophr Bull
Psychiatric disorders are the leading cause of disability worldwide while the pathogenesis remains unclear. Genome-wide association studies (GWASs) have made great achievements in detecting disease-related genetic variants. However, functional inform
Autor:
Detlev Boison, Robert E. McCullumsmith, Ryan C Devore Homan, Cassidy Lynn Moody, Adam J. Funk, Sinead M. O’Donovan, Emily Devine
Publikováno v:
Schizophr Bull
The adenosine hypothesis of schizophrenia posits that reduced availability of the neuromodulator adenosine contributes to dysregulation of dopamine and glutamate transmission and the symptoms associated with schizophrenia. It has been proposed that i