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Publikováno v:
Saudi Pharmaceutical Journal, Vol 26, Iss 1, Pp 53-63 (2018)
A two factor three level factorial design was used to investigate the effects of carbopol and cationic hydrophilic polymers which have a common use in buccal drug formulations. Statistical models with interaction terms were derived to evaluate influe
Autor:
Alexander M. Prusa, Christian A. Plass
Publikováno v:
Saudi Pharmaceutical Journal, Vol 25, Iss 7, Pp 993-998 (2017)
Cigarette smoking not only has a carcinogenic effect but also leads to an increase in arterial blood pressure. Besides its main components, i.e. nicotine, tar, and carbon monoxide, cigarette smoke also contains thiocyanate. Thiocyanate anions (SCN−
Autor:
Saleh Abd El Rasoul, Gamal A. Shazly
Publikováno v:
Saudi Pharmaceutical Journal, Vol 25, Iss 7, Pp 1086-1092 (2017)
Propafenone HCl (PPH), an antiarrhythmic drug, has a bitter taste, short half-life, delayed drug dissolution and side effects. Thus, the purpose of this work is to develop orally fast dissolving tablets (OFDTs) containing PPH to provide a rapid drug
Publikováno v:
Saudi Pharmaceutical Journal, Vol 25, Iss 6, Pp 900-905 (2017)
Caffeine increases the analgesic properties of acetaminophen and therefore it is reasonable to use both substances together in one drug form in stronger pain. Currently, there are no commercially available pharmaceutical combination products containi
Publikováno v:
Saudi Pharmaceutical Journal, Vol 25, Iss 6, Pp 944-953 (2017)
Methoxy poly(ethylene oxide)-block-poly(ɛ-caprolactone) (PEO-b-PCL) copolymers are amphiphilic and biodegradable copolymers designed to deliver a variety of drugs and diagnostic agents. The aim of this study was to synthesize PEO-b-PCL block copolym
Publikováno v:
Saudi Pharmaceutical Journal, Vol 25, Iss 5, Pp 676-687 (2017)
Purpose: Desvenlafaxine succinate (DSV) is a water soluble anti-depressant drug, which is rapidly absorbed after oral administration exaggerating its side effects. The current work aimed to prepare controllable release DSV matrix to reduce DSV side e
Publikováno v:
Saudi Pharmaceutical Journal, Vol 25, Iss 4, Pp 666-670 (2017)
For patients who have sepsis, acute lung injury (ALI) causes most of death. Metformin (Met) is an anti-hyperglycemic agent and it has extensive pharmacological properties. This study aimed to analyze the influence of Met on lipopolysaccharide (LPS) -
Publikováno v:
Saudi Pharmaceutical Journal, Vol 25, Iss 4, Pp 537-547 (2017)
Cistanche is the traditional and precious Chinese herbal, with two thousand years of use history in China. It has the effect on tonifying kidney, strong supplement to the liver and kidney, and replenishing essence and blood, known as the “desert gi
Publikováno v:
Saudi Pharmaceutical Journal, Vol 25, Iss 4, Pp 587-594 (2017)
Endothelium toxicity has been involved in early endothelial dysfunction to show the pathogenesis of multiple cardiovascular disease that shows atherosclerosis and its complications. Saturated free fatty acids are the main inducing factors of endothel
Publikováno v:
Saudi Pharmaceutical Journal, Vol 25, Iss 4, Pp 655-659 (2017)
Saudi Pharm J
Saudi Pharm J
In the present study we compared the clinical efficacy and safety of baclofen vs tolperisone in spasticity caused by spinal cord injury. A total of 150 patients were enrolled in the present study and were divided into two groups with 75 patients in e