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Publikováno v:
Saudi Pharmaceutical Journal, Vol 28, Iss 10, Pp 1290-1300 (2020)
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal : SPJ
Replacing sucrose with non-caloric sweeteners is an approach to avoid overweight and diabetes development. Non-caloric sweeteners are classified into either artificial as sucralose or natural as stevia. Both of them have been approved by FDA, but the
Autor:
Ikram Ullah Khan, Yasser Shahzad, Maimoona Maqbool, Syed A. A. Rizvi, Khadija Majid, Jorabar Singh Nirwan, Yeteng He, Ambreen Aleem, Adnan Younus, Yasir Mehmood, Muhammad Usman Ghori, Abid Mehmood Yousaf, Talib Hussain, Muhammad Arshad
Publikováno v:
Saudi Pharmaceutical Journal, Vol 28, Iss 8, Pp 994-1003 (2020)
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal : SPJ
Rheumatoid arthritis (RA) is an autoimmune disease associated with severe joint pain. Herein, we report lornoxicam loaded cellulosic microsponge gel formulation with sustained anti-inflammatory effects that are required to manage arthritic pain. The
Autor:
Branka I. Ognjanović, Biljana Božić Nedeljković, Emilija Marinković, Bojan Đ. Božić, Miloš M. Matić, Predrag Đurđević, Ana Obradović, Gordana S. Ušćumlić
Publikováno v:
Saudi Pharmaceutical Journal, Vol 28, Iss 3, Pp 246-254 (2020)
Saudi Pharmaceutical Journal
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal
Saudi Pharmaceutical Journal : SPJ
In this study, a series of synthesized 3-(4-substituted benzyl)-5-isopropyl-5-phenylhydantoin derivatives as a potential antiproliferative and antimigratory agents were investigated. The possible antitumor mechanisms of investigated hydantoin derivat
Autor:
Hassan Madkhali
Publikováno v:
Saudi Pharmaceutical Journal, Vol 28, Iss 3, Pp 300-307 (2020)
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal : SPJ
Vascular endothelial dysfunction is caused by dyslipidemia, hypertension, and deficiency of antioxidant systems. In this study, the protective effect of a flavonol, morin was investigated in high-fat diet (HFD)-induced dyslipidemia and vascular endot
Autor:
Moteb Khobrani, Abdulaziz Alhossan, Sultan M. Alshahrani, C. K. Dhanapal, Noohu Abdullah Khan, Sirajudeen Shaik Alavudeen, Javid Iqbal Mir
Publikováno v:
Saudi Pharmaceutical Journal, Vol 28, Iss 2, Pp 210-214 (2020)
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal : SPJ
Introduction: The prevalence of secondary failure to oral hypoglycemic agents among type 2 diabetes mellitus (T2DM) patients ranges from 30 to 60%. The alternative approaches to overcome this issue are either switching to triple oral hypoglycemic age
Autor:
Karol Svik, Ružena Sotníková, Barbara Kaprinay, Lukáš Slovák, Dominika Michalikova, Vladimir Knezl, Boris Lipták, Zdenka Gasparova
Publikováno v:
Saudi Pharmaceutical Journal, Vol 27, Iss 8, Pp 1196-1202 (2019)
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal : SPJ
Background: Metabolic syndrome is a cluster of metabolic risk factors. The clear causes of its development are not known yet and there is no comprehensive treatment of this disease. There is a trend to use natural substances in the treatment of vario
Autor:
Jelena Cvejić Hogervorst, Boris Milijašević, Ana Tomas, Aleksandar Rašković, Tatjana Ćebović, Veljko Ćućuz, Nebojša Stilinović, Ljilja Torović, Ljiljana Gojkovic-Bukarica
Publikováno v:
Saudi Pharmaceutical Journal, Vol 27, Iss 7, Pp 1036-1043 (2019)
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal : SPJ
Graphical abstract
Resveratrol was recognized as the major factor responsible for the beneficial properties of red wine. Several resveratrol-based dietary supplements are available, but their efficacy has not been sufficiently tested. This study
Resveratrol was recognized as the major factor responsible for the beneficial properties of red wine. Several resveratrol-based dietary supplements are available, but their efficacy has not been sufficiently tested. This study
Publikováno v:
Saudi Pharmaceutical Journal, Vol 28, Iss 11, Pp 1408-1410 (2020)
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal : SPJ
Drug-drug interactions lead to altered clinical effects, including adverse reactions. Therapeutic drug monitoring of digoxin is necessary due to its narrow therapeutic range. Linezolid can cause variable exposures in patients hospitalized in the inte
Autor:
Marzena Dworacka, Saule Iskakova, Magdalena Frydrychowicz, Karolina Pomieczyńska, Anna Wesołowska, Agnieszka Stelmaszyk, Grzegorz Dworacki
Publikováno v:
Saudi Pharmaceutical Journal, Vol 26, Iss 8, Pp 1192-1198 (2018)
Introduction: Cardiovascular risk in the course of diabetes depends greatly on glycemic variability which is even more significant than chronic hyperglycemia. Optimal management of diabetes involves a multidisciplinary approach focused in particular
Autor:
Yara M. Zain, Esraa A. Alothman, Saleh I. Alqasoumi, Amal A. Safhi, Reham M. El-Meligy, Shekhah S. Almoqren, Fatmah A.S. Alasmary, Amani S. Awaad
Publikováno v:
Saudi Pharmaceutical Journal, Vol 26, Iss 7, Pp 956-959 (2018)
Sonchus oleraceus L. was evaluated for its gastro antiulcerogenic and anti-ulcerative colitis activities Different extracts and fractions from Sonchus oleraceus aerial parts and roots were evaluated at different dose; total alcohol extracts of aerial