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Publikováno v:
Crabb, TL; Lam, BJ; & Hertel, KJ. (2010). Retention of spliceosomal components along ligated exons ensures efficient removal of multiple introns. RNA, 16(9), 1786-1796. doi: 10.1261/rna.2186510. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2xg3x47h
The majority of mammalian pre-mRNAs contains multiple introns that are excised prior to export and translation. After intron excision, ligated exon intermediates participate in subsequent intron excisions. However, exon ligation generates an exon of