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Autor:
George A W Bruyn, Attila Pethö-Schramm, Ed N. Griep, Michelle E A Borm, Marjolein J H de Hair, Ruth Klaasen, Maxime M A Verhoeven, Jacob M van Laar, Johannes W. J. Bijlsma, Paco M J Welsing, Janneke Tekstra, Floris P J G Lafeber, Reinhard Bos, Johannes W G Jacobs
Publikováno v:
Rheumatology (Oxford, England)
Objectives U-Act-Early was a 2-year, randomized placebo controlled, double-blind trial, in which DMARD-naïve early RA patients were treated to the target of sustained remission (SR). Two strategies initiating tocilizumab (TCZ), with and without meth
Autor:
Zancong Shen, Michael Gillen, Amy Yamamoto, Jesse Hall, Xiaohong Yan, Masanari Shiramoto, Yasushi Ito, Sha Liu
Publikováno v:
Rheumatology (Oxford, England)
Objectives Verinurad (RDEA3170) is a high-affinity inhibitor of the URAT1 transporter in clinical development for treating gout and asymptomatic hyperuricaemia. The aim of this Phase 2a, randomized, open-label study was to investigate the multiple-do