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Autor:
Paul W. Jones, David A. Lipson, Leif Bjermer, Claus Vogelmeier, Isabelle Boucot, Edward Kerwin, François Maltais, Chris Compton, Lee Tombs
Publikováno v:
Respiratory Research
Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)
Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)
Background In patients with chronic obstructive pulmonary disease (COPD), the relationship between short-term bronchodilator reversibility and longer-term response to bronchodilators is unclear. Here, we investigated whether the efficacy of long-acti
Autor:
Félicie Sherer, Serge Goldman, Gaetan Van Simaeys, Amelie Castiaux, Benjamin Bondue, Celine Mathey, Dominique Egrise, Simon Lacroix, François Huaux, Gilles Doumont
Publikováno v:
Respiratory Research
Respiratory Research, Vol 20, Iss 1, Pp 1-11 (2019)
Respiratory research, 20 (1
Respiratory research, Vol. 20, no. 1, p. 10 (2019)
Respiratory Research, Vol 20, Iss 1, Pp 1-11 (2019)
Respiratory research, 20 (1
Respiratory research, Vol. 20, no. 1, p. 10 (2019)
Background: Idiopathic pulmonary fibrosis (IPF) is characterized by a progressive and irreversible respiratory failure. Non-invasive markers of disease activity are essential for prognosis and evaluation of early response to anti-fibrotic treatments.
Autor:
Monika Zurkova, Eva Kriegova, Vitezslav Kolek, Vladimira Lostakova, Martina Sterclova, Vladimir Bartos, Martina Doubkova, Ilona Binkova, Michal Svoboda, Jana Strenkova, Marketa Janotova, Martina Plackova, Ladislav Lacina, Vladimir Rihak, Frantisek Petrik, Pavlina Lisa, Radka Bittenglova, Richard Tyl, Gustav Ondrejka, Hana Suldova, Jaroslav Lnenicka, Jana Psikalova, Tomas Snizek, Jiri Homolka, Renata Kralova, Jan Kervitzer, Martina Vasakova, ILD section, IPF registry
Publikováno v:
Respiratory Research
Respiratory Research, Vol 20, Iss 1, Pp 1-11 (2019)
Respiratory Research, Vol 20, Iss 1, Pp 1-11 (2019)
Introduction Pirfenidone, an antifibrotic drug, slows-down the disease progression in idiopathic pulmonary fibrosis (IPF) over 12 months, however limited data on the decline of lung function and overall survival (OS) in real-world cohorts on longer f
Autor:
Mark Hew, Bruce D. Levy, Shamsah Kazani, Pankaj K. Bhavsar, Elliot Israel, Michael A. Pfeffer, Kian Fan Chung
Publikováno v:
Respiratory Research
Respiratory Research, Vol 11, Iss 1, p 71 (2010)
Respiratory Research, Vol 11, Iss 1, p 71 (2010)
Background An imbalance in the generation of pro-inflammatory leukotrienes, and counter-regulatory lipoxins is present in severe asthma. We measured leukotriene B4 (LTB4), and lipoxin A4 (LXA4) production by alveolar macrophages (AMs) and studied the